Protein Info for NIAGMN_22365 in Escherichia coli ECRC102

Name: wcaA
Annotation: glycosyl transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 248 PF00535: Glycos_transf_2" amino acids 4 to 87 (84 residues), 54.2 bits, see alignment E=9e-19

Best Hits

KEGG orthology group: None (inferred from 100% identity to ece:Z3202)

MetaCyc: 100% identical to GDP-L-fucose:beta-D-Glc-(1->3)-alpha-D-GalNAc-PP-Und alpha-(1,4)-fucosyltranferase (Escherichia coli O157)
2.4.1.-

Predicted SEED Role

"Colanic acid biosynthesis glycosyl transferase WcaE" in subsystem Colanic acid biosynthesis

MetaCyc Pathways

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (248 amino acids)

>NIAGMN_22365 glycosyl transferase (Escherichia coli ECRC102)
MKISVITVTYNNAEGLEKTLSSLSILKIKPFEIIIVDGGSTDGTNRVISRFTSMNITHVY
EKDEGIYDAMNKGRMLAKGDLIHYLNAGDSVIGDIYKNIKEPCLIKVGLFENDKLLGFSS
ITHSNTGYCHQGVIFPKNHSEYDLRYKICADYKLIQEVFPEGLRSLSLITSGYVKYDMGG
VSSKKRILRDKELAKIMFEKNKKNLIKFIPISIIKILFPERLRRVLRKMQYICLTLFFMK
NSSPYDNE