Protein Info for NIAGMN_20425 in Escherichia coli ECRC102

Name: yfcJ
Annotation: Uncharacterized MFS-type transporter YfcJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 392 transmembrane" amino acids 20 to 41 (22 residues), see Phobius details amino acids 48 to 67 (20 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 113 to 139 (27 residues), see Phobius details amino acids 151 to 171 (21 residues), see Phobius details amino acids 177 to 197 (21 residues), see Phobius details amino acids 218 to 243 (26 residues), see Phobius details amino acids 249 to 269 (21 residues), see Phobius details amino acids 279 to 297 (19 residues), see Phobius details amino acids 303 to 327 (25 residues), see Phobius details amino acids 340 to 360 (21 residues), see Phobius details amino acids 367 to 389 (23 residues), see Phobius details PF07690: MFS_1" amino acids 20 to 248 (229 residues), 69.7 bits, see alignment E=1.2e-23 amino acids 223 to 390 (168 residues), 57.3 bits, see alignment E=6.6e-20

Best Hits

Swiss-Prot: 100% identical to YFCJ_ECO57: Uncharacterized MFS-type transporter YfcJ (yfcJ) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 99% identity to eco:b2322)

Predicted SEED Role

"Transporter, putative"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (392 amino acids)

>NIAGMN_20425 Uncharacterized MFS-type transporter YfcJ (Escherichia coli ECRC102)
MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHHDLGYGNTMVGIAVGIQ
FLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAAILPVSAPFKFALLVIGRL
ILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGALAVGAPLGLLIHSHYGFAAL
ALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLIWKPGLGLALQGVGFAVIGTFVS
LYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRFGGVKVAIVSLLVETVGLLLLWQAP
GAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQVRGTALGGYAAFQDIALGVSGPLAGM
LATTFGYSSVFLAGAISAVLGIIVTILSFRRG