Protein Info for NIAGMN_15230 in Escherichia coli ECRC102

Name: secY
Annotation: preprotein translocase subunit SecY

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 443 transmembrane" amino acids 23 to 43 (21 residues), see Phobius details amino acids 75 to 98 (24 residues), see Phobius details amino acids 119 to 140 (22 residues), see Phobius details amino acids 154 to 174 (21 residues), see Phobius details amino acids 185 to 203 (19 residues), see Phobius details amino acids 215 to 237 (23 residues), see Phobius details amino acids 273 to 295 (23 residues), see Phobius details amino acids 316 to 337 (22 residues), see Phobius details amino acids 373 to 391 (19 residues), see Phobius details amino acids 397 to 418 (22 residues), see Phobius details TIGR00967: preprotein translocase, SecY subunit" amino acids 20 to 429 (410 residues), 470.2 bits, see alignment E=2.9e-145 PF00344: SecY" amino acids 76 to 417 (342 residues), 402.8 bits, see alignment E=5.3e-125

Best Hits

Swiss-Prot: 100% identical to SECY_SHIFL: Protein translocase subunit SecY (secY) from Shigella flexneri

KEGG orthology group: K03076, preprotein translocase subunit SecY (inferred from 100% identity to eco:b3300)

MetaCyc: 100% identical to Sec translocon subunit SecY (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

"Preprotein translocase secY subunit (TC 3.A.5.1.1)" (TC 3.A.5.1.1)

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (443 amino acids)

>NIAGMN_15230 preprotein translocase subunit SecY (Escherichia coli ECRC102)
MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGIDAAVLAKLLEQQRGTI
IEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTLAEIKKEGESGRRKISQYT
RYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTAVVSLVTGTMFLMWLGEQITE
RGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFLVLLLVAVLVFAVTFFVVFVERG
QRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIPAIFASSIILFPATIASWFGGGTGW
NWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTALVFNPRETADNLKKSGAFVPGIRPGE
QTAKYIDKVMTRLTLVGALYITFICLIPEFMRDAMKVPFYFGGTSLLIVVVVIMDFMAQV
QTLMMSSQYESALKKANLKGYGR