Protein Info for NIAGMN_14090 in Escherichia coli ECRC102

Name: chuU
Annotation: heme permease protein ChuU

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 318 signal peptide" amino acids 1 to 19 (19 residues), see Phobius details transmembrane" amino acids 44 to 64 (21 residues), see Phobius details amino acids 73 to 95 (23 residues), see Phobius details amino acids 104 to 122 (19 residues), see Phobius details amino acids 134 to 155 (22 residues), see Phobius details amino acids 176 to 204 (29 residues), see Phobius details amino acids 225 to 250 (26 residues), see Phobius details amino acids 264 to 283 (20 residues), see Phobius details amino acids 294 to 312 (19 residues), see Phobius details PF01032: FecCD" amino acids 6 to 313 (308 residues), 321.7 bits, see alignment E=2.3e-100

Best Hits

Swiss-Prot: 67% identical to HMUU_YERPE: Hemin transport system permease protein HmuU (hmuU) from Yersinia pestis

KEGG orthology group: K02015, iron complex transport system permease protein (inferred from 99% identity to eum:ECUMN_4006)

Predicted SEED Role

"Hemin ABC transporter, permease protein" in subsystem Hemin transport system or Iron acquisition in Vibrio or Putative hemin transporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (318 amino acids)

>NIAGMN_14090 heme permease protein ChuU (Escherichia coli ECRC102)
MGLSLLLLALVLFGASQGALKISFDALFDEEYRDIWLNIRLPRVLLAVLVGAALATAGVI
MQGLFRNPMADPGLLGVSSGSALMVGVAIVLPFSFPVVLVLYEQMVFAIAGSLVVCAIIF
LITQRHRDGSMMQLLLAGIAINALCGAAIGILSYIGDEQQLRQLTLWMMGNLGQAQWPTL
LVASSFILPAIIATTCLAGTLNLLQLGDEEAHYLGVNVKRKRQQLLLVSSLLVGAAVSVS
GIIGFIGLVIPHLIRMTTGANHRWLIPCSALAGACLLLMADTLARTLVQPAEMPVGLLTS
LLGGPYFMWLILRNRRIT