Protein Info for NIAGMN_14075 in Escherichia coli ECRC102

Name: hdeB
Annotation: acid-activated periplasmic chaperone HdeB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 112 signal peptide" amino acids 1 to 34 (34 residues), see Phobius details PF06411: HdeA" amino acids 19 to 100 (82 residues), 89.6 bits, see alignment E=6.5e-30

Best Hits

Swiss-Prot: 99% identical to HDEB_ECOL6: Acid stress chaperone HdeB (hdeB) from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC)

KEGG orthology group: None (inferred from 98% identity to eok:G2583_4244)

Predicted SEED Role

"Chaperone HdeB"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (112 amino acids)

>NIAGMN_14075 acid-activated periplasmic chaperone HdeB (Escherichia coli ECRC102)
MGYKINISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFIDLNPKAMTPVAWW
MLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQASNDLPN