Protein Info for NIAGMN_13950 in Escherichia coli ECRC102

Name: tadD
Annotation: Flp pilus assembly protein TadD, contains TPR repeats

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 100 200 300 400 500 600 700 800 900 1002 PF13432: TPR_16" amino acids 119 to 181 (63 residues), 29.1 bits, see alignment 6e-10 amino acids 201 to 263 (63 residues), 34.9 bits, see alignment 9.1e-12 amino acids 234 to 295 (62 residues), 24.4 bits, see alignment 1.7e-08 amino acids 452 to 508 (57 residues), 17.2 bits, see alignment 3e-06 PF13181: TPR_8" amino acids 149 to 179 (31 residues), 25.5 bits, see alignment (E = 4.8e-09) PF07719: TPR_2" amino acids 149 to 180 (32 residues), 23.2 bits, see alignment (E = 2.5e-08) PF13176: TPR_7" amino acids 150 to 179 (30 residues), 18.5 bits, see alignment (E = 8.5e-07) PF14559: TPR_19" amino acids 458 to 527 (70 residues), 38.1 bits, see alignment 8e-13 PF05420: BCSC_C" amino acids 647 to 981 (335 residues), 401.9 bits, see alignment E=1.2e-123

Best Hits

Swiss-Prot: 100% identical to BCSC_ECO57: Putative cellulose synthase operon protein C (bcsC) from Escherichia coli O157:H7

KEGG orthology group: None (inferred from 100% identity to ecs:ECs4410)

Predicted SEED Role

"Cellulose synthase operon protein C"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (1002 amino acids)

>NIAGMN_13950 Flp pilus assembly protein TadD, contains TPR repeats (Escherichia coli ECRC102)
VAKIPARRGEAINQLKRINADEPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGRE
GASKIWYGQIKDMPVSDASVSALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQ
GLAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDPH
SSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLGDVA
MARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRRSIDDI
ERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQAGQRSQAD
TLMRNLAQQKPNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWSSNIQELVNRLQSDQ
VLETANRLRESGKEAEAEAMLRQQPPSTRIDLTLADWALQRRDYTAARAAYQNVLTREPT
NADAILGLTEVDIAAGDTAAARSQLAKLPATDNASLNTQRRVALAQAQLGDTAAAQQTFN
KLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPKQALETYKDAMVASGVTTTRPQDNDTFT
RLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGTGGYSDLKAHTTMLQVDA
PYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLRDCSGNRSQSDSGASVAVGWRN
DVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAHRRPISSSLLAFGGQKDFPSNT
GKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTGKNVEDNWRVRWMTGYYYKVINQN
NRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEYLSFAIPVMWRERTENWSWELGASGS
WSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDGGSSQGFGYTARALLERRVTSNWFVGTA
IDIQQAKDYAPSHFLLYVRYSAAGWQGDMDLPPQPLIPYADW