Protein Info for NIAGMN_12235 in Escherichia coli ECRC102

Name: aslA
Annotation: arylsulfatase AslA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 551 signal peptide" amino acids 1 to 25 (25 residues), see Phobius details PF00884: Sulfatase" amino acids 86 to 418 (333 residues), 241.1 bits, see alignment E=8.9e-76

Best Hits

Swiss-Prot: 99% identical to ASLA_ECOLI: Putative sulfatase AslA (aslA) from Escherichia coli (strain K12)

KEGG orthology group: K01130, arylsulfatase [EC: 3.1.6.1] (inferred from 99% identity to eco:b3801)

MetaCyc: 99% identical to putative sulfatase AslA (Escherichia coli K-12 substr. MG1655)

Predicted SEED Role

No annotation

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.6.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (551 amino acids)

>NIAGMN_12235 arylsulfatase AslA (Escherichia coli ECRC102)
MEFSFSPKLLVVAVAAALPLMASAADTPSTATARKGFAGYDHPNQYLVKPATTIADNMMP
VMQHPAQDKEPQQKLAELEKKTGKKPNVVVFLLDDVGWMDVGFNGGGVAVGNPTPDIDAV
ASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMYGQPGGLQGLTTLPQLLHDQG
YVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYTEWRDVHVNPEVALSPDRSEYIK
QLPFSKDDVHAVRGGEQQAIADITPKYMEDLDQRWMEYGVKFLDKMAKSDKPFFLYYGTR
GCHFDNYPNAKYAGSSPARTSYGDCMVEMNDVFANLYKALEKNGQLDNTLIVFTSDNGPE
AEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWKGMIQPRKSDGIVDLADLFPTALDLAGHP
GAKVANLVPKTTFIDGVDQTSFFLGTNGQSNRKAEHYFLNGKLAAVRMDEFKYHVLIQQP
YAYTQSGYQGGFTGTVMQTAGSSVFNLYTDPQESDSIGVRHIPMGVPLQTEMHAYMEILK
KYPPRAQIKSD