Protein Info for NIAGMN_09225 in Escherichia coli ECRC102

Name: tsr
Annotation: methyl-accepting chemotaxis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 554 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details transmembrane" amino acids 192 to 214 (23 residues), see Phobius details PF02203: TarH" amino acids 1 to 176 (176 residues), 185.7 bits, see alignment E=1.1e-58 PF00672: HAMP" amino acids 217 to 263 (47 residues), 45.6 bits, see alignment 1.1e-15 PF00015: MCPsignal" amino acids 327 to 484 (158 residues), 210.1 bits, see alignment E=3.2e-66

Best Hits

Swiss-Prot: 99% identical to MCP1_ECOLI: Methyl-accepting chemotaxis protein I (tsr) from Escherichia coli (strain K12)

KEGG orthology group: K05874, methyl-accepting chemotaxis protein I, serine sensor receptor (inferred from 99% identity to ecx:EcHS_A4586)

Predicted SEED Role

"Methyl-accepting chemotaxis protein I (serine chemoreceptor protein)" in subsystem Bacterial Chemotaxis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (554 amino acids)

>NIAGMN_09225 methyl-accepting chemotaxis protein (Escherichia coli ECRC102)
MLKRIKIVTSLLLVLAVFGLLQLTSGGLFFNALKNDKENFTVLQTIRQQQSTLNGSWVAL
LQTRNTLNRAGIRYMMDQNNIGSGSTVAELMQSASISLKQAEKNWADYEALPRDPRQSTA
AAAEIKRNYDIYHNALAELIQLLGAGKINEFFDQPTQGYQDGFEKQYVAYMEQNDRLYDI
AVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKP
IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAA
SLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVVQTMRDISTSSQK
IADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSL
IEDSVGKVDVGSTLVESAGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEM
DRVTQQNAALVEESAAAAAALEEQASRLTEAVAVFRIQQQQQQQRETSAVVKTVTPATPR
KMAVADSGENWETF