Protein Info for NIAGMN_08195 in Escherichia coli ECRC102

Name: dksA
Annotation: RNA polymerase-binding protein DksA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 151 TIGR02420: RNA polymerase-binding protein DksA" amino acids 32 to 140 (109 residues), 171.3 bits, see alignment E=3.8e-55 PF21157: DksA_CC" amino acids 36 to 106 (71 residues), 117.1 bits, see alignment E=3.3e-38 PF01258: zf-dskA_traR" amino acids 110 to 143 (34 residues), 42.4 bits, see alignment 5.6e-15

Best Hits

Swiss-Prot: 100% identical to DKSA_SHIFL: RNA polymerase-binding transcription factor DksA (dksA) from Shigella flexneri

KEGG orthology group: K06204, DnaK suppressor protein (inferred from 100% identity to eco:b0145)

Predicted SEED Role

"C4-type zinc finger protein, DksA/TraR family"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (151 amino acids)

>NIAGMN_08195 RNA polymerase-binding protein DksA (Escherichia coli ECRC102)
MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRILEAWRNQLRDEVDRTVT
HMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKTLKKVEDEDFGYCESCGVE
IGIRRLEARPTADLCIDCKTLAEIREKQMAG