Protein Info for NIAGMN_03590 in Escherichia coli ECRC102

Annotation: adenine/guanine phosphoribosyltransferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 380 PF15609: PRTase_2" amino acids 33 to 220 (188 residues), 213.1 bits, see alignment E=2.6e-67 PF12500: TRSP" amino acids 265 to 364 (100 residues), 82.2 bits, see alignment E=3.1e-27

Best Hits

KEGG orthology group: None (inferred from 100% identity to eoj:ECO26_1306)

Predicted SEED Role

"COG0503: Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (380 amino acids)

>NIAGMN_03590 adenine/guanine phosphoribosyltransferase (Escherichia coli ECRC102)
MSDILEDMIYRRTLSCGTIQVTRDQGEVSLDDLFDIAERRNPKRAFLFVSKVLGRHIPVP
PSVMRQAYRQLASQFPSTLTGPVLFIGMAETAVGLGAGVFDEVRHQHRESVYLTSTRHPV
DGTLLCEFKEEHSHATDHLIYLPDDEEKRRRVTNARTLVLIDDEATTGNTFINLLSALRN
TGKLQHIEQVIAVTLTDWSGNALSERTPLPVTSVSLVSGQWGWTPLPDAPVPDMPKVNVT
SRGEWDIQGKQSWGRLGMLAPAADLGHEVSVHKGERILVLGTGEFVWEPFLLAERLEAAG
AQAFYGSTTRSPVAVGYAIESAISFTDNYGLGIPNFVYNVAHQQFDRILVCTETPAESID
TQLLKALAEVAPVVEIVTYE