Protein Info for NIAGMN_02690 in Escherichia coli ECRC102

Annotation: lysis protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 155 signal peptide" amino acids 1 to 21 (21 residues), see Phobius details PF03245: Phage_lysis" amino acids 30 to 153 (124 residues), 159.2 bits, see alignment E=2.9e-51

Best Hits

Swiss-Prot: 87% identical to SPAN1_BP933: Spanin, inner membrane subunit (Rz) from Enterobacteria phage 933W

KEGG orthology group: None (inferred from 99% identity to eoh:ECO103_2397)

Predicted SEED Role

"putative endopeptidase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (155 amino acids)

>NIAGMN_02690 lysis protein (Escherichia coli ECRC102)
MNRVLCVVIIVLLVACGALSLGLNHYRDHAIIYKEQRDKKASELELANATITDMQIRQRD
VAALDARYSRELADARAENETLRADVAAGRKRLRINATCSGTVREATGTSGVDNATGPRL
ADTAERDYFILRERLMAMQKQLEGAQEYIRTQCIP