Protein Info for NIAGMN_01655 in Escherichia coli ECRC102

Name: copD
Annotation: copper homeostasis membrane protein CopD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 290 transmembrane" amino acids 6 to 30 (25 residues), see Phobius details amino acids 50 to 73 (24 residues), see Phobius details amino acids 93 to 110 (18 residues), see Phobius details amino acids 118 to 138 (21 residues), see Phobius details amino acids 152 to 172 (21 residues), see Phobius details amino acids 192 to 215 (24 residues), see Phobius details amino acids 226 to 248 (23 residues), see Phobius details amino acids 269 to 287 (19 residues), see Phobius details PF05425: CopD" amino acids 185 to 284 (100 residues), 94.6 bits, see alignment E=2.2e-31

Best Hits

Swiss-Prot: 99% identical to YEBZ_ECOLI: Inner membrane protein YebZ (yebZ) from Escherichia coli (strain K12)

KEGG orthology group: K07245, putative copper resistance protein D (inferred from 99% identity to eco:b1840)

Predicted SEED Role

"Copper resistance protein D" in subsystem Copper homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (290 amino acids)

>NIAGMN_01655 copper homeostasis membrane protein CopD (Escherichia coli ECRC102)
MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLTKRFLRLQQHAAVWSLISATA
MLAVQGGLMGTGWKDVFSPNIWQAVLQTQFGGVWLWQIVLALVTLIVALMQPRNMPRLLF
MLTTAQFILLAGVGHATLNEGVTAKIHQTNHAIHLICAAAWFGGLLPVLWCMQLIKGRWR
HQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPTLTTYWGQLLLLKAILVMIMVVI
ALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAVVLLIISLLATLEPF