Protein Info for MPMX26_03165 in Acinetobacter radioresistens SK82

Annotation: Thiol-disulfide oxidoreductase ResA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 281 transmembrane" amino acids 12 to 32 (21 residues), see Phobius details amino acids 53 to 71 (19 residues), see Phobius details amino acids 90 to 106 (17 residues), see Phobius details amino acids 118 to 135 (18 residues), see Phobius details PF01790: LGT" amino acids 6 to 108 (103 residues), 44.1 bits, see alignment E=4.9e-15 PF08534: Redoxin" amino acids 142 to 266 (125 residues), 56.9 bits, see alignment E=6.5e-19 PF00578: AhpC-TSA" amino acids 156 to 258 (103 residues), 50.8 bits, see alignment E=4.9e-17 PF13098: Thioredoxin_2" amino acids 168 to 274 (107 residues), 27.1 bits, see alignment E=1.3e-09 PF13905: Thioredoxin_8" amino acids 168 to 255 (88 residues), 33.6 bits, see alignment E=1.2e-11 PF00085: Thioredoxin" amino acids 169 to 274 (106 residues), 27.6 bits, see alignment E=7.1e-10

Best Hits

Predicted SEED Role

"Thioredoxin" in subsystem Glycine reductase, sarcosine reductase and betaine reductase

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (281 amino acids)

>MPMX26_03165 Thiol-disulfide oxidoreductase ResA (Acinetobacter radioresistens SK82)
MISSEALHLGPLMLPWTLIIILIGLMTVSIIGQMVSNKLRWDKAVIQVFRDSLWISVLIG
LIGARIVFVLLHWDAYSTSPLDIFKIQDKGFHLIGGIVTAIPYFLWKNKGLPGKSKAIFI
FIFTLLLSLGIAFQNNLKQETHFPDLSFSSLIQHGEISENVPLKQFIGQPTVINMWASWC
PPCHREMPVLQQAHNQYPGINFVMLNQGEDQVTVQDYLRRYDLKFKHVLLDPYGEIPQQM
NMFGLPSTLFFNAQGQLVERHMGELSPAMLQQYLKKISIQP