Protein Info for MPMX26_03083 in Acinetobacter radioresistens SK82

Annotation: tRNA(fMet)-specific endonuclease VapC

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 131 transmembrane" amino acids 98 to 110 (13 residues), see Phobius details PF01850: PIN" amino acids 3 to 124 (122 residues), 75.1 bits, see alignment E=3.7e-25

Best Hits

Swiss-Prot: 48% identical to VAPC2_RICFE: Ribonuclease VapC2 (vapC2) from Rickettsia felis (strain ATCC VR-1525 / URRWXCal2)

KEGG orthology group: None (inferred from 68% identity to dno:DNO_1042)

Predicted SEED Role

"VapC toxin protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (131 amino acids)

>MPMX26_03083 tRNA(fMet)-specific endonuclease VapC (Acinetobacter radioresistens SK82)
MIYLLDTNICIYVINHKPEHVFERFKQYQLGQLAISSITASELAFGVEKSGSERNKQALN
KFLSPLDILPYDEKAIWHYAKLRQDLQSTGKIIGSLDMLIAAHALALDVVLVTNNIKEFE
RIDGLKLENWV