Protein Info for MPMX26_02934 in Acinetobacter radioresistens SK82

Annotation: UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 365 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details TIGR01133: undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase" amino acids 9 to 362 (354 residues), 348.8 bits, see alignment E=1.6e-108 PF03033: Glyco_transf_28" amino acids 12 to 148 (137 residues), 144 bits, see alignment E=3.4e-46 PF04101: Glyco_tran_28_C" amino acids 195 to 356 (162 residues), 135.1 bits, see alignment E=2.5e-43

Best Hits

Swiss-Prot: 80% identical to MURG_ACIBT: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (murG) from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377)

KEGG orthology group: K02563, UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase [EC: 2.4.1.227] (inferred from 80% identity to aby:ABAYE0148)

Predicted SEED Role

"UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (EC 2.4.1.227)" in subsystem Peptidoglycan Biosynthesis (EC 2.4.1.227)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.4.1.227

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (365 amino acids)

>MPMX26_02934 UDP-N-acetylglucosamine--N-acetylmuramyl- (pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase (Acinetobacter radioresistens SK82)
MSDSQQRISKHVMIMAAGTGGHVFPALAVAKQLQSEGAQVSWLATPQGMENRLLQDQKIP
IYQIDIQGVRGNGILRKLMAPFKILKATFSAMRYMKQLKIDAVAGFGGYVAGPGGLAARL
LGIPVIIHEQNAVAGFTNIQLSRIAKIVCQAFPETFSPQSKVVTTGNPVRKEIAEILNPK
WRYDQRAAAQAPLNILIVGGSLGAQALNERVPAVLKQFDMPLKVFHQCGQKQLELTQSAY
QGAPASLQVEVQPFITDMAKAYSDADLIICRAGALTVTEVATAGVAAIFVPLPIAVDNHQ
TANARFLADLGAAKICQQAVMSPEYLKELLTPLLNRQLLTEMAVKARQQAQPNATQHVVD
LIKKL