Protein Info for MPMX26_02887 in Acinetobacter radioresistens SK82

Annotation: General stress protein 39

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF00106: adh_short
  • amino acids 43 to 236 (194 residues), 162.5 bits, E=1.3e-51
• PF08659: KR
  • amino acids 45 to 207 (163 residues), 56.7 bits, E=4.8e-19
• PF13561: adh_short_C2
  • amino acids 51 to 283 (233 residues), 205.4 bits, E=1.6e-64

Best Hits

Swiss-Prot: 59% identical to YHXC_BACSU: Uncharacterized oxidoreductase YhxC (yhxC) from Bacillus subtilis (strain 168)

KEGG orthology group: None (inferred from 75% identity to acd:AOLE_11765)

MetaCyc: 48% identical to aldehyde reductase (chloroplastic) (Arabidopsis thaliana col)
Aldehyde reductase. [EC: 1.1.1.21]; Alcohol dehydrogenase (NADP(+)). [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.2 [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]; 1.1.1.- [EC: 1.1.1.21, 1.1.1.2]

Predicted SEED Role

"3-oxoacyl-[acyl-carrier protein] reductase (EC 1.1.1.100)" in subsystem Fatty Acid Biosynthesis FASII or mycolic acid synthesis (EC 1.1.1.100)

MetaCyc Pathways

• superpathway of fatty acids biosynthesis (E. coli) (47/53 steps found)
• superpathway of fatty acid biosynthesis II (plant) (38/43 steps found)
• palmitate biosynthesis II (type II fatty acid synthase) (29/31 steps found)
• oleate biosynthesis IV (anaerobic) (13/14 steps found)
• superpathway of fatty acid biosynthesis I (E. coli) (14/16 steps found)
• biotin biosynthesis I (13/15 steps found)
• superpathway of unsaturated fatty acids biosynthesis (E. coli) (16/20 steps found)
• palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate) (8/9 steps found)
• fatty acid elongation -- saturated (5/5 steps found)
• gondoate biosynthesis (anaerobic) (4/4 steps found)
• 8-amino-7-oxononanoate biosynthesis I (9/11 steps found)
• (5Z)-dodecenoate biosynthesis I (5/6 steps found)
• stearate biosynthesis II (bacteria and plants) (5/6 steps found)
• 8-amino-7-oxononanoate biosynthesis IV (4/5 steps found)
• octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast) (9/12 steps found)
• palmitate biosynthesis III (21/29 steps found)
• (5Z)-dodecenoate biosynthesis II (4/6 steps found)
• stearate biosynthesis IV (4/6 steps found)
• methylglyoxal degradation III (1/2 steps found)
• cis-vaccenate biosynthesis (3/5 steps found)
• superpathway of methylglyoxal degradation (5/8 steps found)
• tetradecanoate biosynthesis (mitochondria) (17/25 steps found)
• pyruvate fermentation to butanol I (4/8 steps found)
• D-xylose degradation to ethylene glycol (engineered) (1/4 steps found)
• L-tryptophan degradation X (mammalian, via tryptamine) (1/4 steps found)
• superpathway of Clostridium acetobutylicum solventogenic fermentation (7/13 steps found)
• glycerol degradation to butanol (9/16 steps found)
• detoxification of reactive carbonyls in chloroplasts (4/10 steps found)
• superpathway of Clostridium acetobutylicum acidogenic and solventogenic fermentation (9/17 steps found)
• petroselinate biosynthesis (1/6 steps found)
• 2-allylmalonyl-CoA biosynthesis (2/8 steps found)
• streptorubin B biosynthesis (20/34 steps found)
• anteiso-branched-chain fatty acid biosynthesis (19/34 steps found)
• even iso-branched-chain fatty acid biosynthesis (19/34 steps found)
• odd iso-branched-chain fatty acid biosynthesis (19/34 steps found)
• traumatin and (Z)-3-hexen-1-yl acetate biosynthesis (3/12 steps found)
• superpathway of lipoxygenase (4/22 steps found)
• superpathway of pentose and pentitol degradation (5/42 steps found)
• mycolate biosynthesis (22/205 steps found)
• superpathway of mycolate biosynthesis (23/239 steps found)

KEGG Metabolic Maps

• Biosynthesis of unsaturated fatty acids
• Caprolactam degradation
• Fatty acid biosynthesis
• Fructose and mannose metabolism
• Galactose metabolism
• Glycerolipid metabolism
• Glycolysis / Gluconeogenesis
• Pentose and glucuronate interconversions
• Pyruvate metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.100

Use Curated BLAST to search for 1.1.1.100 or 1.1.1.2 or 1.1.1.21

Protein Sequence (288 amino acids)

>MPMX26_02887 General stress protein 39 (Acinetobacter radioresistens SK82)
MNQYPATPPAQIQTHQPGKQTKMNPEPEIIKASHKGSDKLKDKVALITGGDSGIGRSVAV
LFAREGADIVIAYLEESQDAEDTKAMVEQEGRRCLLVKCDIQKKEDVDQLVEKALNEFQK
INILVNNAGVQYPQKYLTDIPQQQLFKTFETNIFSMFYLTQAVLPYLKEGDSIINTTSIT
SYHGHDQLIDYSSTKGAITSFTRSLSTNLLKNKTGIRVNGVAPGPIWTPLIPSSFDEEQV
KDFGKETPMERMGQPSEVAPAYLFLASDDASYISGQVIHVNGGSIVNG