Protein Info for MPMX26_02750 in Acinetobacter radioresistens SK82

Annotation: 3-methylmercaptopropionyl-CoA dehydrogenase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 607 transmembrane" amino acids 523 to 541 (19 residues), see Phobius details PF12418: AcylCoA_DH_N" amino acids 4 to 27 (24 residues), 32.5 bits, see alignment (E = 2.2e-11) PF02771: Acyl-CoA_dh_N" amino acids 37 to 157 (121 residues), 60.6 bits, see alignment E=5.6e-20 PF02770: Acyl-CoA_dh_M" amino acids 163 to 272 (110 residues), 48.1 bits, see alignment E=3.2e-16 PF00441: Acyl-CoA_dh_1" amino acids 282 to 457 (176 residues), 72.2 bits, see alignment E=1.6e-23 PF22924: ACOX_C_alpha1" amino acids 327 to 449 (123 residues), 29 bits, see alignment E=2.7e-10 PF12806: Acyl-CoA_dh_C" amino acids 474 to 598 (125 residues), 100.3 bits, see alignment E=2.5e-32

Best Hits

KEGG orthology group: K00257, [EC: 1.3.99.-] (inferred from 90% identity to aci:ACIAD3262)

Predicted SEED Role

"Acyl-CoA dehydrogenase (EC 1.3.8.7)" (EC 1.3.8.7)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.3.8.7, 1.3.99.-

Use Curated BLAST to search for 1.3.8.7 or 1.3.99.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (607 amino acids)

>MPMX26_02750 3-methylmercaptopropionyl-CoA dehydrogenase (Acinetobacter radioresistens SK82)
MPAYKAPLRDTRFLMNEVFDYPAHYQTLSNGELADSDTVDMILEGAADYCENVISPLYQT
GDDEGCHWNNGEVTTPKGYKEAYDQFVQSGWQGLSYPEQYGGQGLPMSLNLIKSEMMGTA
NWAFTMYPGLSMGCMNTILQFGTEEQKDIYMPPLVAGTWSGTMCLTEPQCGTDLGQLKTK
AEPQADSTYKITGTKIFISAGEHDLTENIVHIVLARLPDAPAGTKGISLFIVPKFLPTAE
GSVGERNAVNCGSIEHKMGIKASATAVLNFDNATGYLIGEQNKGLHAMFTFMNTARIGTA
VQGIAHAELSFQGALPYAKERMSMRALSGKKDPEKVADAIIHHADVRRMLLTQKAIAEGG
RAMIYHAAQLADKMTDALARGDNAEYEEYDDKLGFYTPILKGFLTELGLEAANHGMQVFG
GHGYIKEWGMEQIVRDARIATLYEGTTGVQALDLIGRKVLLSSKGKVVRDYTAEILKFSG
RHARNKYMRRFAWDLTKICAQWNALTVRIMLAARKDRDIVSSASFDYLMFSGYAMMAYFW
AQQAAVASEKLESGEGKETPEFYKAKIKVADFYFERMLPRAQGHAEAMVNPSRTMTSLAA
EHFSFDY