Protein Info for MPMX26_02724 in Acinetobacter radioresistens SK82

Annotation: Cystathionine beta-lyase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF01053: Cys_Met_Meta_PP
  • amino acids 8 to 394 (387 residues), 257.5 bits, E=7.8e-81

Best Hits

KEGG orthology group: K01760, cystathionine beta-lyase [EC: 4.4.1.8] (inferred from 76% identity to acd:AOLE_02075)

Predicted SEED Role

"Cystathionine beta-lyase (EC 4.4.1.8)" in subsystem Methionine Biosynthesis (EC 4.4.1.8)

MetaCyc Pathways

• hydrogen sulfide biosynthesis II (mammalian) (1/6 steps found)

KEGG Metabolic Maps

• Biosynthesis of plant hormones
• Cysteine metabolism
• Methionine metabolism
• Nitrogen metabolism
• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 4.4.1.8

Protein Sequence (397 amino acids)

>MPMX26_02724 Cystathionine beta-lyase (Acinetobacter radioresistens SK82)
MSKIQNKQTCLVHAPRKAPQYIETVQPPLFRASTIIFKNTDALFNRHWTDAYDYSYGTHG
TPTTFTLADNIAQIEGGQHSLLTPSGLSAINLVNSCFLSHGDEVWVPDNIYGPNMEHLRN
LHQRYGIEVKIYNALEHESFQPTSKTKLLWLEAAGSVSLEFPDLKRLVRKARQSGILTAL
DNTWGAGLAFNAFDFSDEHLSVDLTVHALTKYPSGGADILMGSVVTRDRKLYQQLFRMHA
IQGISISGDDAAQIQRSLAHMQLRYQQQSTNTIVLLNWLKQQPEFVQVLHPADENSPGHQ
YWKETCIDKQSAGLVSVIFKPEYDLESVRKFCDQLRLFKLGFSWGGPVSLVMLYQLKEMR
TLECTHLKEGVLVRFCIGLEAVDDLITDIQQALQVLR