Protein Info for MPMX26_02559 in Acinetobacter radioresistens SK82

Annotation: Transcriptional regulatory protein RstA

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 238 PF00072: Response_reg" amino acids 10 to 119 (110 residues), 89.7 bits, see alignment E=1.5e-29 PF00486: Trans_reg_C" amino acids 156 to 231 (76 residues), 85.8 bits, see alignment E=1.8e-28

Best Hits

Swiss-Prot: 42% identical to WALR_STAES: Transcriptional regulatory protein WalR (walR) from Staphylococcus epidermidis (strain ATCC 12228)

KEGG orthology group: K07661, two-component system, OmpR family, response regulator RstA (inferred from 99% identity to acd:AOLE_15945)

Predicted SEED Role

"Transcriptional regulatory protein RstA" in subsystem Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (238 amino acids)

>MPMX26_02559 Transcriptional regulatory protein RstA (Acinetobacter radioresistens SK82)
MSQEEKLPKILIVEDDERLARLTQEYLIRNGLEVGVETDGNRAIRRIISEQPDMVVLDVM
LPGADGLTVCREVRPHYHQPILMLTARTEDMDQVLGLEMGADDYVPKPVQPRVLLARIRA
LLRRTDKTVEDEVAQRIEFDDLVIDNGGRSVTLNGELVDFTSAEYDLLWLLASNAGRILS
REDIFERLRGIEYDGQDRSIDVRISRIRPKIGDDPENPKRIKTVRSKGYLFVKETNGL