Protein Info for MPMX26_02545 in Acinetobacter radioresistens SK82

Annotation: NADH-quinone oxidoreductase subunit L

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 630 signal peptide" amino acids 1 to 22 (22 residues), see Phobius details transmembrane" amino acids 31 to 52 (22 residues), see Phobius details amino acids 64 to 81 (18 residues), see Phobius details amino acids 87 to 106 (20 residues), see Phobius details amino acids 113 to 132 (20 residues), see Phobius details amino acids 138 to 158 (21 residues), see Phobius details amino acids 170 to 192 (23 residues), see Phobius details amino acids 206 to 227 (22 residues), see Phobius details amino acids 249 to 273 (25 residues), see Phobius details amino acids 279 to 300 (22 residues), see Phobius details amino acids 307 to 325 (19 residues), see Phobius details amino acids 333 to 354 (22 residues), see Phobius details amino acids 374 to 397 (24 residues), see Phobius details amino acids 421 to 446 (26 residues), see Phobius details amino acids 458 to 478 (21 residues), see Phobius details amino acids 509 to 531 (23 residues), see Phobius details amino acids 553 to 573 (21 residues), see Phobius details amino acids 607 to 629 (23 residues), see Phobius details TIGR01974: proton-translocating NADH-quinone oxidoreductase, chain L" amino acids 4 to 622 (619 residues), 680.6 bits, see alignment E=1.5e-208 PF00662: Proton_antipo_N" amino acids 67 to 117 (51 residues), 68.4 bits, see alignment 3.9e-23 PF00361: Proton_antipo_M" amino acids 134 to 411 (278 residues), 284.3 bits, see alignment E=1.1e-88

Best Hits

KEGG orthology group: K00341, NADH dehydrogenase I subunit L [EC: 1.6.5.3] (inferred from 88% identity to aci:ACIAD0741)

Predicted SEED Role

"NADH-ubiquinone oxidoreductase chain L (EC 1.6.5.3)" in subsystem Respiratory Complex I (EC 1.6.5.3)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 1.6.5.3

Use Curated BLAST to search for 1.6.5.3

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (630 amino acids)

>MPMX26_02545 NADH-quinone oxidoreductase subunit L (Acinetobacter radioresistens SK82)
MSYLYLTVLFPLIGFLLLAAGRDKLSENISAVIGAGSVGLSALIALIAGMEFVGNGSVAQ
VQHLWTWFSVGTFAPGISLHLDGLSLLMTGMITGVGFLIHIFASWYMRGEEGYARFFSYF
NLFVASMLLLVLGDNLALLFLGWEGVGLCSYLLIGFYYSNPANGWAAIKAFTVTRVGDVF
LLIALFLLYQQFGTLNIQYIVANAAQVMTLSSSLSIWTALMLFLGAAGKSAQIPLQTWLA
DAMAGPTPVSALIHAATMVTAGVYLTCRMFAVMEMAPEVMQFISITGAVTLLVAGFAALV
QTDIKRILAYSTMSQLGYMFMAVGAEAYQAGLFHMLAHAFFKALLFLSSGAVILACHHEQ
NIFKMGGLRKKIPFVFWCFVIGGGALAALPIVTVGFFSKDAILGAVYAQSAMSNLPLYNT
LYWVGVGGAFLTSIYTFRLIWVVFFGEEKTHAHEIKGVTYWGPLAILAALSTGLGYFLQG
PVNKLLATAIPAFSIPETLEDAVAHAEHLASGVAIAGLIVGIILFAFAYNVVKSIANTSF
GTGIANIWRNAFGFDALYHLVFVKPYLLIAKIMGRDPIDSLWLVLPALVKSGNSFTSSRQ
TGLLREYASSMSLGVVVLLMILIVIQVVGK