Protein Info for MPMX26_02237 in Acinetobacter radioresistens SK82
Annotation: Elongation factor P--(R)-beta-lysine ligase
These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.
Protein Families and Features
Best Hits
KEGG orthology group: K04568, lysyl-tRNA synthetase, class II [EC: 6.1.1.6] (inferred from 80% identity to aby:ABAYE0854)Predicted SEED Role
"Translation elongation factor P Lys34:lysine transferase"
MetaCyc Pathways
- tRNA charging (20/21 steps found)
- myxochelin A and B biosynthesis (1/9 steps found)
KEGG Metabolic Maps
Isozymes
Compare fitness of predicted isozymes for: 6.1.1.6
Use Curated BLAST to search for 6.1.1.6
Sequence Analysis Tools
PaperBLAST (search for papers about homologs of this protein)
Search CDD (the Conserved Domains Database, which includes COG and superfam)
Compare to protein structures
Predict protein localization: PSORTb (Gram-negative bacteria)
Predict transmembrane helices and signal peptides: Phobius
Check the current SEED with FIGfam search
Find homologs in fast.genomics or the ENIGMA genome browser
Find the best match in UniProt
Protein Sequence (324 amino acids)
>MPMX26_02237 Elongation factor P--(R)-beta-lysine ligase (Acinetobacter radioresistens SK82) MKHSYQPTCTLEVMRARATMYTQIRQFFAERNVLEVETPVLSQAGVTDVHLASVSAQRHV EGKLQIHYLQTSPEFTMKRLLASGSGPIYQICKVFRDDEHGRKHNSEFTMLEWYRPGFSL LDLMHETTALLNICLVQRFGEMRPVVISYKHAFQDRLDINPLQASVKLLKDTANRLGINL DLGDDRLAYIDLLFSHFVEPSLGFDAPVFLTDFPPELASLAKVKTDEDGEQVAARFELYI EGLELANAYDELIDSKVLRERFEADNTERCTLGLPVMPIDENLLTALQYMPECSGIALGI DRLLMIATRQMRLENVITFPAQIA