Protein Info for MPMX26_02234 in Acinetobacter radioresistens SK82

Annotation: D-serine/D-alanine/glycine transporter

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 467 transmembrane" amino acids 25 to 42 (18 residues), see Phobius details amino acids 53 to 75 (23 residues), see Phobius details amino acids 97 to 123 (27 residues), see Phobius details amino acids 137 to 156 (20 residues), see Phobius details amino acids 166 to 188 (23 residues), see Phobius details amino acids 212 to 234 (23 residues), see Phobius details amino acids 254 to 273 (20 residues), see Phobius details amino acids 288 to 311 (24 residues), see Phobius details amino acids 348 to 367 (20 residues), see Phobius details amino acids 373 to 397 (25 residues), see Phobius details amino acids 416 to 436 (21 residues), see Phobius details amino acids 442 to 461 (20 residues), see Phobius details PF00324: AA_permease" amino acids 24 to 464 (441 residues), 375.1 bits, see alignment E=4.9e-116 PF13520: AA_permease_2" amino acids 27 to 454 (428 residues), 146.3 bits, see alignment E=1.4e-46

Best Hits

Swiss-Prot: 62% identical to CYCA_ECO57: D-serine/D-alanine/glycine transporter (cycA) from Escherichia coli O157:H7

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 86% identity to aby:ABAYE0858)

MetaCyc: 62% identical to D-serine/alanine/glycine:H+symporter (Escherichia coli K-12 substr. MG1655)
RXN0-5130; RXN0-5201; RXN0-5202; RXN0-5203; TRANS-RXN-62A; TRANS-RXN-62B

Predicted SEED Role

"D-serine/D-alanine/glycine transporter" in subsystem Glycine and Serine Utilization or Pyruvate Alanine Serine Interconversions

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (467 amino acids)

>MPMX26_02234 D-serine/D-alanine/glycine transporter (Acinetobacter radioresistens SK82)
MSNQMHSSIPEEEGELKRSLSNRHLQLIAIGGAIGTGLFMGSGKTISLAGPSILFIYMII
GVMVFLVMRALGELLLSNLHYKSFIDFSADLIGPWAGYFVGWTYWLCWITIGIADLSAII
YYLQFFNNGLPFTPLEGVLISIASIVFIMGLNLVTVKLFGEMEFWFALIKIIAIVVLIAV
GLWMIFTGFTSTAGEVASFTNLWSHDGLFPTGMSGFLAGFQIAIFAFVGVELVGTTAAET
KDPERNLPKAVNSIPIRIIIFYVLALLIVMSVTPWNKIDPNISPFVNLFSQAGVAAAAII
MNLVVLSSVMSSMNSGVFSTSRMLFGLSREAQAPRWFGKLTSRAIPANALYFSAVCLLLG
AALQYFVPNAVQAFTLATTLSTILFICVWIIIMWSYINYRKQRPELHAKSIFKLPGGVFT
CWVVIIFFIGMVYVLSLEADTFQALKVSPLWLIILAIGYFFTKSKKS