Protein Info for MPMX26_02142 in Acinetobacter radioresistens SK82

Annotation: UvrABC system protein B

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 673 TIGR00631: excinuclease ABC subunit B" amino acids 7 to 668 (662 residues), 1062.7 bits, see alignment E=0 PF04851: ResIII" amino acids 18 to 88 (71 residues), 47 bits, see alignment E=1e-15 PF17757: UvrB_inter" amino acids 161 to 251 (91 residues), 119.8 bits, see alignment E=1.6e-38 PF27431: UvrB_3rd" amino acids 257 to 317 (61 residues), 99.4 bits, see alignment 2.9e-32 PF00271: Helicase_C" amino acids 436 to 546 (111 residues), 75 bits, see alignment E=2e-24 PF12344: UvrB" amino acids 553 to 594 (42 residues), 72.7 bits, see alignment 6.1e-24 PF02151: UVR" amino acids 639 to 670 (32 residues), 34.2 bits, see alignment (E = 5.4e-12)

Best Hits

Swiss-Prot: 90% identical to UVRB_ACIAD: UvrABC system protein B (uvrB) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K03702, excinuclease ABC subunit B (inferred from 91% identity to abm:ABSDF0970)

MetaCyc: 68% identical to UvrABC excision nuclease subunit B (Escherichia coli K-12 substr. MG1655)
3.1.25.-

Predicted SEED Role

"Excinuclease ABC subunit B" in subsystem DNA repair, UvrABC system

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (673 amino acids)

>MPMX26_02142 UvrABC system protein B (Acinetobacter radioresistens SK82)
MSESRPFELVTQYAPAGDQPQAIEKLVKGIQQGYKSQLLLGVTGSGKTYTMANVIAQTQR
PTIVMAHNKTLAAQLYGEFKAFFPNNAVEYFVSYYDYYQPEAYVPSSDTFIEKDAAINDH
IDQMRLSATRSLLERRDAIIVASVSAIYGLGDPEAYMKMLLHIVQGDRVGRDDIIRRLVE
MQYTRNELEFVRGTYRIRGEIMDIFPAESEQNAIRIELFDDEVDSIRWFDPLTGKMLRKV
PRVTIYPKSHYVTPKDNLVRAIDTIRDELKDQLKFFREHDKLLEAQRIEQRTRYDLEMMQ
QLGYTNGIENYSRHLSGRRPGDAPPTLFDYVPDDALLIIDESHVTVPQIGAMYKGDRSRK
ENLVNYGFRLPSALDNRPMKFEEWERIIPTTVFVSATPARYELEKSEQVVEQVVRPTGLI
DPEIEIRPVLTQVDDVLSEINIRKNLNERVLVTTLTKRMAEDLTAYLKEYGVKVAYLHSD
IDTVERVKIIHELRTGVFDVLVGINLLREGLDMPEVSLVAILDADKEGFLRSERSLIQTI
GRAARNIKGKAILYADRITDSMQKAIDETERRRNKQIEFNELHGIIPRSAVRQVIKEIDT
GEVLAEDEIDEKITAQALSLTADERHILADPKLLSKHMAKLEKEMLKASKELQFEQAARL
RDEILRLKAQMLQ