Protein Info for MPMX26_02013 in Acinetobacter radioresistens SK82

Annotation: Alkyl hydroperoxide reductase subunit F

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 521 TIGR03140: alkyl hydroperoxide reductase subunit F" amino acids 1 to 518 (518 residues), 774.7 bits, see alignment E=1.9e-237 PF13192: Thioredoxin_3" amino acids 119 to 194 (76 residues), 35.9 bits, see alignment E=2.2e-12 PF07992: Pyr_redox_2" amino acids 212 to 505 (294 residues), 171.9 bits, see alignment E=7.3e-54 PF01134: GIDA" amino acids 213 to 243 (31 residues), 20.8 bits, see alignment (E = 6.6e-08) PF13738: Pyr_redox_3" amino acids 259 to 488 (230 residues), 72.5 bits, see alignment E=1.3e-23 PF00070: Pyr_redox" amino acids 357 to 430 (74 residues), 45.4 bits, see alignment E=3.3e-15

Best Hits

Swiss-Prot: 66% identical to AHPF_PSEPU: Alkyl hydroperoxide reductase subunit F (ahpF) from Pseudomonas putida

KEGG orthology group: K03387, alkyl hydroperoxide reductase subunit F [EC: 1.6.4.-] (inferred from 85% identity to abb:ABBFA_002377)

MetaCyc: 61% identical to alkyl hydroperoxide reductase, AhpF component (Escherichia coli K-12 substr. MG1655)
RXN-8506 [EC: 1.5.1.37]; R4-RXN [EC: 1.5.1.37, 1.11.1.26]

Predicted SEED Role

"Alkyl hydroperoxide reductase protein F (EC 1.6.4.-)" in subsystem Thioredoxin-disulfide reductase (EC 1.6.4.-)

Isozymes

Compare fitness of predicted isozymes for: 1.6.4.-

Use Curated BLAST to search for 1.11.1.26 or 1.5.1.37 or 1.6.4.-

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (521 amino acids)

>MPMX26_02013 Alkyl hydroperoxide reductase subunit F (Acinetobacter radioresistens SK82)
MLDQNTSAQLKTLLERLESPIELVASLDGSDKSDKIKELVNEIAALSDQVTARLDGQHSR
RPSFGVAKAGEQPRVFFAGLPMGHEFTSLILALLQVSGYAPKVSDEVLAQIKALNLTADF
EVFVSLSCHNCPDVVQALNLIAIYNPGTTATMIDGAFFQEEVEQRKIMAVPMLFQNSQHI
GQGRMTLEEIIAKLDSGAAAKDAEKLNAKAAFDVLVIGGGPAGNTAAIYAARKGIRTGIV
AERFGGQVMDTMDIENFTSVTKTQGPKFAAAMEEHVREYEVDIMNLQKVASIKGAEETAN
GLVEVTLDNGARLESKTVILSTGARWRQMNVPGEQEYATRGVAYCPHCDGPLFKGKRVAV
IGGGNSGVEAAIDLAGIVEHVTLLEFADTLRADQVLQDKLASLPNTTVIKSALTTEVVGD
GSQVTALRYQDRVSGEDREIELAGIFVQIGLLPNTDFLKGSEVELSNRGEIVVNERNETN
VKGVFAAGDCTTVPYKQIIIATGEGAKASLSAFDYIIRSGQ