Protein Info for MPMX26_01969 in Acinetobacter radioresistens SK82

Annotation: Arabinose 5-phosphate isomerase KdsD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 325 PF01380: SIS" amino acids 41 to 172 (132 residues), 92.5 bits, see alignment E=1.9e-30 TIGR00393: sugar isomerase, KpsF/GutQ family" amino acids 45 to 314 (270 residues), 348.8 bits, see alignment E=1.2e-108 PF00571: CBS" amino acids 201 to 257 (57 residues), 29.2 bits, see alignment E=9.6e-11 amino acids 269 to 322 (54 residues), 48.8 bits, see alignment 7.3e-17

Best Hits

Swiss-Prot: 55% identical to KDSD_FRATT: Arabinose 5-phosphate isomerase KdsD (kdsD) from Francisella tularensis subsp. tularensis (strain SCHU S4 / Schu 4)

KEGG orthology group: K06041, arabinose-5-phosphate isomerase [EC: 5.3.1.13] (inferred from 86% identity to abn:AB57_1409)

MetaCyc: 59% identical to D-arabinose 5-phosphate isomerase KdsD (Escherichia coli K-12 substr. MG1655)
Arabinose-5-phosphate isomerase. [EC: 5.3.1.13]

Predicted SEED Role

"Arabinose 5-phosphate isomerase (EC 5.3.1.13)" in subsystem KDO2-Lipid A biosynthesis (EC 5.3.1.13)

MetaCyc Pathways

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.3.1.13

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (325 amino acids)

>MPMX26_01969 Arabinose 5-phosphate isomerase KdsD (Acinetobacter radioresistens SK82)
MTQQIDFQKVARETLQIEQQALEILAAQIDTRFERACEIILQCKGRVVVTGMGKSGHIGR
KMAATFASTGTPSFFMHPGEAGHGDLGMLVRGDVLIAISNSGKSDEIMMLMPLIKHLEVP
LITISGTESGPMPQNADVALTLGELTEACPLGLAPTSSTTATLALGDALAVALLEARGFT
ADDFARSHPAGALGKRLLLHVKHLMHKDDELPKVSPDTPMNQVLYEISNKRLGLTTVVDT
QNTLLGIFTDGDLRRLIDRQQGFDVNLPVSEVMIKDPYTISQEARAVEALELLRDKKINQ
FVVVDQSNKVIGVISMHDLIQAGVN