Protein Info for MPMX26_01927 in Acinetobacter radioresistens SK82

Annotation: Glycine cleavage system transcriptional activator

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 304 PF00126: HTH_1" amino acids 7 to 68 (62 residues), 62.2 bits, see alignment E=3.7e-21 PF03466: LysR_substrate" amino acids 92 to 301 (210 residues), 122.9 bits, see alignment E=1.3e-39

Best Hits

KEGG orthology group: K03566, LysR family transcriptional regulator, glycine cleavage system transcriptional activator (inferred from 64% identity to bam:Bamb_6449)

Predicted SEED Role

"Glycine cleavage system transcriptional activator GcvA" in subsystem Glycine cleavage system or Orphan regulatory proteins

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (304 amino acids)

>MPMX26_01927 Glycine cleavage system transcriptional activator (Acinetobacter radioresistens SK82)
MKTPVYLNALRAFEASARHQSFSTAAIELNVTPAAVGQLVKSLEDYLGITLFQRSTGGKA
RLVVTEAALMALPDIRAGFNRLLLGLEKLQAQTSAGVLTVAISPAFASKWLLPRIDTFQQ
AYPEIDIRLDTNLEPVDFAQHGIDIAVRYGQGNWSGLVAEKLMDEEVFPVCSPGFYQKYR
HLLKYVENLLNLPLIHDLTLDVHTGFTTWNTWLKYNQVSNGLAQRGLKINNSAAVLQAAI
DGHGVALARSVMVADDLKTGQLIRLYPDMKYSSALAYYIVYRQECQNKPKFVAFKTWLMD
EVKL