Protein Info for MPMX26_01874 in Acinetobacter radioresistens SK82

Annotation: D-methionine transport system permease protein MetI

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 231 signal peptide" amino acids 1 to 23 (23 residues), see Phobius details transmembrane" amino acids 37 to 57 (21 residues), see Phobius details amino acids 77 to 96 (20 residues), see Phobius details amino acids 98 to 121 (24 residues), see Phobius details amino acids 163 to 186 (24 residues), see Phobius details amino acids 205 to 227 (23 residues), see Phobius details PF00528: BPD_transp_1" amino acids 63 to 228 (166 residues), 64.1 bits, see alignment E=7.1e-22

Best Hits

Swiss-Prot: 47% identical to METI_VIBCH: Probable D-methionine transport system permease protein MetI (metI) from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)

KEGG orthology group: K02072, D-methionine transport system permease protein (inferred from 90% identity to aby:ABAYE1363)

MetaCyc: 47% identical to L-methionine/D-methionine ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
RXN0-4522 [EC: 7.4.2.11]; 7.4.2.11 [EC: 7.4.2.11]; TRANS-RXN-383 [EC: 7.4.2.11]; TRANS-RXN0-510 [EC: 7.4.2.11]; TRANS-RXN0-511 [EC: 7.4.2.11]

Predicted SEED Role

"Methionine ABC transporter permease protein" in subsystem Methionine Biosynthesis or Methionine Degradation

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.4.2.11

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (231 amino acids)

>MPMX26_01874 D-methionine transport system permease protein MetI (Acinetobacter radioresistens SK82)
MRDLIVQWLTSVTAPFWKSSLSIDQFVTALQETFHMVFFAMLFGCVWGFIQGITLVVTRP
GGILPNRLIYHGLNPIVNALRSLPFIILLIAVIPLTKLLVGTSIGTWAAIVPLTIYVGPY
IGRLVETSLLEVNEGIIESAQAMGATPLQIIFNFILPEARSSLILNLTTATISLIGATAM
AGAVGAGGIGDLAISYGYQRFDTSVVILTVIVLLILVQIVQMLGEWLARLR