Protein Info for MPMX26_01739 in Acinetobacter radioresistens SK82

Annotation: 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF12146: Hydrolase_4
  • amino acids 83 to 318 (236 residues), 117 bits, E=1.3e-37
• PF00561: Abhydrolase_1
  • amino acids 87 to 312 (226 residues), 53.7 bits, E=3.6e-18
• PF12697: Abhydrolase_6
  • amino acids 90 to 289 (200 residues), 41.8 bits, E=3e-14

Best Hits

KEGG orthology group: None (inferred from 88% identity to acd:AOLE_07015)

Predicted SEED Role

"Lysophospholipase (EC 3.1.1.5)" in subsystem Triacylglycerol metabolism (EC 3.1.1.5)

MetaCyc Pathways

• phospholipid remodeling (phosphatidylethanolamine, yeast) (2/4 steps found)

KEGG Metabolic Maps

• Glycerophospholipid metabolism

Isozymes

Compare fitness of predicted isozymes for: 3.1.1.5

Use Curated BLAST to search for 3.1.1.5

Protein Sequence (343 amino acids)

>MPMX26_01739 2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase (Acinetobacter radioresistens SK82)
MSDIPFLNPNVLTQLDLPIPSREITSQLLEPLNLNRPYEPSVDILAYRKLYGLNLLYCDQ
WQGYVPMPLFRLHVQVFKPRVAEIKGTVCLLHGYLEHSGIYQPIIREILEQGFSVITYDL
PGHGLSDGSPANIQNFDHYQQVLLAVYQYVRQADQLPQPWLGIGQSTGGAIWMHHLLEYA
EQRRNPIVDRILLLSPLIRPAKTAWWHNPVGLGIIRRIKRQVPRHFRRNNHNPEFLRFIR
LKDPLQPRMMGMDWILAMSRWMQEMEQRPACRIPVWLAQGALDQTVDWRYNIEFIRRKFR
LQTLLMLEEGSHQLINERADIRAALTGLIPAFLHARPSKYYYE