Protein Info for MPMX26_01553 in Acinetobacter radioresistens SK82

Annotation: Transcriptional repressor PaaX

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 312 PF07848: PaaX" amino acids 20 to 86 (67 residues), 85.9 bits, see alignment E=2.6e-28 TIGR02277: phenylacetic acid degradation operon negative regulatory protein PaaX" amino acids 22 to 304 (283 residues), 269.4 bits, see alignment E=2.1e-84 PF20803: PaaX_M" amino acids 105 to 176 (72 residues), 26.8 bits, see alignment E=6.8e-10 PF08223: PaaX_C" amino acids 193 to 281 (89 residues), 83.4 bits, see alignment E=1.8e-27

Best Hits

KEGG orthology group: K02616, phenylacetic acid degradation operon negative regulatory protein (inferred from 60% identity to abc:ACICU_01346)

Predicted SEED Role

"Phenylacetic acid degradation operon negative regulatory protein PaaX"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (312 amino acids)

>MPMX26_01553 Transcriptional repressor PaaX (Acinetobacter radioresistens SK82)
MNPKLKQVIDDFISNEPLSGTSLIMTVFGDCIFHRGGIISLASLIQLMDVFGFNERSVRT
AVFRLAQNGWLISEKIGRTSYYRVTESSRQRFVNADQKIYNLSHKEWDQKWDLVLLSSVE
LENKIILKKELEWLGFANIATNVMAYPGCDHLKLQSLLLNLKMSDQVVLFKAEALELWQE
SYPTVKRMVETNWPVQELHQRYEKFIGDFREVLNLIESIDDLDPIQAFQIRILLIHQYRR
ILLKDPNLPFELLPSNWLSLTARNLSSNVYQMVFHPAEDFFLELARTAEGSMPPAHPQFY
KRFGGLKQEVTI