Protein Info for MPMX26_01474 in Acinetobacter radioresistens SK82

Annotation: Aromatic amino acid transport protein AroP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 transmembrane" amino acids 20 to 36 (17 residues), see Phobius details amino acids 42 to 61 (20 residues), see Phobius details amino acids 97 to 119 (23 residues), see Phobius details amino acids 125 to 143 (19 residues), see Phobius details amino acids 152 to 173 (22 residues), see Phobius details amino acids 194 to 219 (26 residues), see Phobius details amino acids 239 to 260 (22 residues), see Phobius details amino acids 280 to 299 (20 residues), see Phobius details amino acids 331 to 351 (21 residues), see Phobius details amino acids 357 to 378 (22 residues), see Phobius details amino acids 398 to 420 (23 residues), see Phobius details amino acids 426 to 444 (19 residues), see Phobius details PF00324: AA_permease" amino acids 17 to 451 (435 residues), 403.4 bits, see alignment E=1.3e-124 PF13520: AA_permease_2" amino acids 21 to 422 (402 residues), 139.6 bits, see alignment E=1.5e-44

Best Hits

Swiss-Prot: 63% identical to AROP_ECOLI: Aromatic amino acid transport protein AroP (aroP) from Escherichia coli (strain K12)

KEGG orthology group: K03293, amino acid transporter, AAT family (inferred from 80% identity to abc:ACICU_03609)

MetaCyc: 63% identical to aromatic amino acid:H+ symporter AroP (Escherichia coli K-12 substr. MG1655)
TRANS-RXN-56; TRANS-RXN-76; TRANS-RXN-77

Predicted SEED Role

"Aromatic amino acid transport protein AroP" in subsystem Aromatic amino acid degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>MPMX26_01474 Aromatic amino acid transport protein AroP (Acinetobacter radioresistens SK82)
MDNPQQGDLNAGLKNRHIQLIALGGAIGTGLFLGISQTIKMAGPSVILGYAIAGLIAFLM
MRQLGEMIVEEPVSGSFSHFAYKYWGKFAGFMSGWNYWVLNVLVCMAELSAIGLYIHYWW
PEIPTWMTALGFFILINGINLLHVKFFGEMEFWLAIIKVVAIICMIGFGSYLLTTGSAGP
QSTISNLWALGGFFPNGISGLVMAMAVIMFAFGGIELVGIAAAETHEPGKTLPKAINQIV
YRILIFYIGTLVVILSLFPWNKMAEGGSPFVLIFDSLNSQGVATVLNFVVLTAAVSVYNS
TSYCTSRMLLGLAKQGNAPEFLSKINKNGIPVPAVLISAFVTLLCVLLNYMFPEKAFSLL
MMLVVAAIVINWMVIFITHLKFRKQMIRENKTTQFPSLAYPFTNYLCIVFMIGILGIMIM
TPDMRIAVMMIPGWLLCLLIAYQIKKRKALQRHNMVLETDT