Protein Info for MPMX26_01297 in Acinetobacter radioresistens SK82

Annotation: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 249 TIGR00055: di-trans,poly-cis-decaprenylcistransferase" amino acids 9 to 236 (228 residues), 280.9 bits, see alignment E=3.3e-88 PF01255: Prenyltransf" amino acids 16 to 236 (221 residues), 259.4 bits, see alignment E=1.3e-81

Best Hits

Swiss-Prot: 75% identical to UPPS_ACIAD: Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (uppS) from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)

KEGG orthology group: K00806, undecaprenyl diphosphate synthase [EC: 2.5.1.31] (inferred from 78% identity to abn:AB57_2318)

MetaCyc: 46% identical to ditrans,polycis-undecaprenyl-diphosphate synthase [(2E,6E)-farnesyl-diphosphate specific] (Escherichia coli K-12 substr. MG1655)
Di-trans,poly-cis-decaprenylcistransferase. [EC: 2.5.1.31]

Predicted SEED Role

"Undecaprenyl diphosphate synthase (EC 2.5.1.31)" (EC 2.5.1.31)

MetaCyc Pathways

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 2.5.1.31

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (249 amino acids)

>MPMX26_01297 Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) (Acinetobacter radioresistens SK82)
MTASEEKHLPEHVAIIMDGNNRFAKKNQMQKGEGHREGKNVLDPIVECCVEQGVKALTVF
AFSSENWNRPQFEVELLMSLLEETIHDQMPRMEKFDICLRFIGDRSRLPAHLRELMLQAE
QRTANFSTMTLVIAVSYGGMWDIAEAAKQIAQDAVNQKIQIEDINVDLFGQYASLGDLPP
VDLLIRTGGDYRLSNFLLWQAAYAELYFTPTLWPEFTVNEFNHALNIFNSRERRFGKTSE
QIQQKKLEN