Protein Info for MPMX26_01059 in Acinetobacter radioresistens SK82

Annotation: Lon protease

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 750 800 850 877 PF20437: LonC_helical" amino acids 126 to 158 (33 residues), 53.4 bits, see alignment (E = 4.1e-18) PF13654: AAA_32" amino acids 356 to 486 (131 residues), 160.4 bits, see alignment E=4.6e-51 PF20436: LonB_AAA-LID" amino acids 515 to 579 (65 residues), 68.7 bits, see alignment 7.2e-23 PF05362: Lon_C" amino acids 689 to 795 (107 residues), 39.1 bits, see alignment E=1.2e-13

Best Hits

KEGG orthology group: None (inferred from 84% identity to abn:AB57_2857)

Predicted SEED Role

"ATP-dependent protease La (EC 3.4.21.53) Type II" in subsystem Proteasome bacterial or Proteolysis in bacteria, ATP-dependent (EC 3.4.21.53)

Isozymes

Compare fitness of predicted isozymes for: 3.4.21.53

Use Curated BLAST to search for 3.4.21.53

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (877 amino acids)

>MPMX26_01059 Lon protease (Acinetobacter radioresistens SK82)
MTQRLDQMTSSLSTTTTINLEKQLDHAYPSALDRTEIQNTLNLTTLKPEQLTHIPDLEKI
PSSTKRIKPLNNFLGQDRAKASVEAGITLPYSGYNIFAVGTAGLGKRTMIRRLLQQHAKA
MPTPDDWVYVNNFENARQPILLRFPAGHGPKFQKALHQTWQVALKQLERRFSAETYHNQI
ELIRQQTGNEQQQALVELTREGEGLDLKLVSHQEQHCFVPVQIKDGKLEELSQTEINALS
SKERAEIASNMRYMDKKLERLGLHLGDLEDEARDQVSDLNREIAKQVVMPRIESILNKYA
EVAGLEKYLKQYAENIIENVEMILDQEEDEFSPALFSRVPSRYQVNTIVSNKPNSGAPVI
FEDFPTHYNLLGHVEQLTQNGTISTDFSLIRPGALHKANGGFLILEAEQLLEQPYAWQGL
KRALKSGQLKLSSLEHMLTLTGSISIEPAPVPLNLKVVLLAEPEIYYEILEVEPELDSIF
KIRADFTDTLQRNDTNEQAYMQLIADYVQADKLLPFDRSALAALLTDSSRQAEDQSSLSL
HALTLGDLIREAHHHAHQAGDKVVSAKYINMALDHRKYRLGYLRELYWQDLSRGTQLIET
SGHRLGQINALSVIHYADVEFGLPSRLTASVYQGGGDILDIERSVELGGSLHAKGVLLMS
SFLKAHFGREQMLHFSAALAFEQSYGQVDGDSATVAELSALLSAISQIPIDQSWAITGSM
NQLGQVQPVGGVNAKIEGFFDACKLQGLTGKQGVIIPRQNMQHLMLRQDVIDAVNAGQFH
VHAISTIDQALEILMAQPVGTLDKKGRYSKGSIYAAVMEQLEYWQALEDGEEMSEEPKKK
KKKKKKKKKNEVKIAIEGNTVDQIPAGNISAELSGQP