Protein Info for MPMX26_01054 in Acinetobacter radioresistens SK82

Annotation: 5'-nucleotidase SurE

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00087: 5'/3'-nucleotidase SurE
  • amino acids 1 to 242 (242 residues), 221.6 bits, E=5.6e-70
• PF01975: SurE
  • amino acids 3 to 186 (184 residues), 192.9 bits, E=2.5e-61

Best Hits

Swiss-Prot: 85% identical to SURE_ACIBY: 5'-nucleotidase SurE (surE) from Acinetobacter baumannii (strain AYE)

KEGG orthology group: K03787, 5'-nucleotidase [EC: 3.1.3.5] (inferred from 85% identity to abc:ACICU_02639)

Predicted SEED Role

"5-nucleotidase SurE (EC 3.1.3.5)" in subsystem Folate Biosynthesis (EC 3.1.3.5)

MetaCyc Pathways

• purine nucleotides degradation II (aerobic) (9/11 steps found)
• guanosine nucleotides degradation III (3/4 steps found)
• inosine 5'-phosphate degradation (3/4 steps found)
• UTP and CTP dephosphorylation I (5/7 steps found)
• NAD salvage pathway III (to nicotinamide riboside) (2/3 steps found)
• adenosine nucleotides degradation II (3/5 steps found)
• guanosine nucleotides degradation II (2/4 steps found)
• ureide biosynthesis (4/7 steps found)
• guanosine nucleotides degradation I (1/4 steps found)
• superpathway of guanosine nucleotides degradation (plants) (2/6 steps found)
• adenosine nucleotides degradation I (3/8 steps found)
• NAD salvage (plants) (5/11 steps found)
• purine nucleotides degradation I (plants) (5/12 steps found)
• tunicamycin biosynthesis (2/9 steps found)
• superpathway of purines degradation in plants (6/18 steps found)

KEGG Metabolic Maps

• Biosynthesis of alkaloids derived from histidine and purine
• Nicotinate and nicotinamide metabolism
• Purine metabolism
• Pyrimidine metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.1.3.5

Protein Sequence (257 amino acids)

>MPMX26_01054 5'-nucleotidase SurE (Acinetobacter radioresistens SK82)
MNILIANDDGVFAPGLQALAQALKPLGRVVVVAPEAERSGYSSALTLDRPLRPVPIAEDV
WAVNGTPADCVYLSMNGLFDFEFDLVVSGINSGANLGDDVLYSGTVGAAFEGRLMKQPAI
AVSLAGGNVRSYVHPDEFKVAARWVHDFIARGLPQLPPRHILNINIPDLQELKGAQITYQ
GQRSQSKPITSHVDPRGRQVYWIGLAGEAVTEPRENIHQIQSDFFAIANGYVSITPIQMD
ATNYAILESLQTDLELS