Protein Info for MPMX26_00920 in Acinetobacter radioresistens SK82

Annotation: UDP-N-acetylglucosamine 2-epimerase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR00236: UDP-N-acetylglucosamine 2-epimerase
  • amino acids 4 to 374 (371 residues), 422.3 bits, E=8.6e-131
• PF02350: Epimerase_2
  • amino acids 26 to 373 (348 residues), 354.2 bits, E=3.4e-110

Best Hits

KEGG orthology group: K01791, UDP-N-acetylglucosamine 2-epimerase [EC: 5.1.3.14] (inferred from 62% identity to aci:ACIAD1175)

Predicted SEED Role

"UDP-N-acetylglucosamine 2-epimerase (EC 5.1.3.14)" in subsystem CMP-N-acetylneuraminate Biosynthesis or Sialic Acid Metabolism (EC 5.1.3.14)

MetaCyc Pathways

• UDP-N-acetyl-α-D-mannosamine biosynthesis (1/1 steps found)
• CMP-N-acetylneuraminate biosynthesis II (bacteria) (1/3 steps found)
• CMP-N-acetylneuraminate biosynthesis I (eukaryotes) (1/5 steps found)
• superpathway of UDP-N-acetylglucosamine-derived O-antigen building blocks biosynthesis (8/24 steps found)
• superpathway of CMP-sialic acids biosynthesis (1/15 steps found)

KEGG Metabolic Maps

• Aminosugars metabolism
• Nucleotide sugars metabolism

Isozymes

No predicted isozymes

Use Curated BLAST to search for 5.1.3.14

Protein Sequence (382 amino acids)

>MPMX26_00920 UDP-N-acetylglucosamine 2-epimerase (Acinetobacter radioresistens SK82)
MPIHISFIFGTRPELIKLAPVILQARQDFRFEVSVVFTGQHLELVRDAIDFFQIEIDHHL
QVMQPGKSLNILLSTALTELDRVYTQMSKCDAIVVQGDTTTVLAGALVAFNLNIGLAHVE
AGLRSFDLLHPFPEEGNRQLVSRLARWHFAPTALSASNLLQENVPEEHIFVTGNTVVDAI
YSAREIMQASSQQSQQRLKRLSLNPQEKNKLVLITAHRRENFGQGIQNICQAIHELCQRY
PELHFAWPVHLNPHVHTVAHQEFAQHPQVHLLSPLDYPDLLAILQASYLIMTDSGGIQEE
SPTYQKPVLILRDVTERPEVVEAGCGVLVGTDVTKIVQEFSRLMDDHSYYLQHAEVENPF
GDGRASGRILEQIIKDLNPVSS