Protein Info for MPMX26_00614 in Acinetobacter radioresistens SK82

Annotation: Sulfite reductase [ferredoxin]

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF03460: NIR_SIR_ferr
  • amino acids 53 to 109 (57 residues), 66.1 bits, 1.9e-22
  • amino acids 341 to 396 (56 residues), 46.4 bits, 2.7e-16
• PF01077: NIR_SIR
  • amino acids 119 to 274 (156 residues), 149.6 bits, E=5.1e-48
  • amino acids 408 to 543 (136 residues), 48 bits, E=9.7e-17

Best Hits

KEGG orthology group: K00392, sulfite reductase (ferredoxin) [EC: 1.8.7.1] (inferred from 91% identity to aci:ACIAD2982)

Predicted SEED Role

"Sulfite reductase [NADPH] hemoprotein beta-component (EC 1.8.1.2)" in subsystem Cysteine Biosynthesis (EC 1.8.1.2)

MetaCyc Pathways

• superpathway of L-methionine biosynthesis (by sulfhydrylation) (11/12 steps found)
• superpathway of sulfate assimilation and cysteine biosynthesis (8/9 steps found)
• assimilatory sulfate reduction III (3/3 steps found)
• assimilatory sulfate reduction I (3/4 steps found)
• assimilatory sulfate reduction IV (3/4 steps found)
• assimilatory sulfate reduction II (2/3 steps found)
• superpathway of sulfur amino acid biosynthesis (Saccharomyces cerevisiae) (6/10 steps found)

KEGG Metabolic Maps

• Selenoamino acid metabolism
• Sulfur metabolism

Isozymes

Compare fitness of predicted isozymes for: 1.8.1.2

Use Curated BLAST to search for 1.8.1.2 or 1.8.7.1

Protein Sequence (547 amino acids)

>MPMX26_00614 Sulfite reductase [ferredoxin] (Acinetobacter radioresistens SK82)
MYLYTDFDQQLVNERVAQFRDQTERYLAGKLTEDEYRPLRLQNGLYVQRYAPMLRMAVPY
GLMNSKQLRKIAEISKKYDRGYAHVSTRQNIQLNWPALEDVPDILAELATVQMHAIQTSG
NCIRNTTTDQYAGVVAGEIADPRPTCELIRQWSTFHPEFAFLPRKFKIAVSALAEVDRAA
TAFHDIGVYIIRNAQGELGYKIMVGGGLGRTPIIGSVIREFLPREDLIAYLEAVLRVYNL
HGRRDNKYKARIKILVKALTPQVFAEKVEAEFAHTRESLKIQPEVLKKLDEEFTPFDYQN
LADEDFAELFEAHPKFKHWFNINTHAHKVQGYRIVTISLKRAGVAPGDMTTEEMNLIADL
ADRYTFGELRTTHEQNIALVDVPQKDLFELWQTLDAQNLARAHIGFLTDIICCPGGDFCS
LANAKSIPIAEAITRRFEDLDTLYNLGQLDLNISGCMNACGHHHVGNIGILGVDKKGAEF
YQITLGGNADHDASIGDILGPSFAAEVVPDIIEEILNTYLDLRTDNEKFIDTYRRVGIQT
FKERAYA