Protein Info for MPMX26_00543 in Acinetobacter radioresistens SK82

Annotation: Poly(A) polymerase I

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 483 TIGR01942: poly(A) polymerase" amino acids 6 to 410 (405 residues), 398.7 bits, see alignment E=1.5e-123 PF01743: PolyA_pol" amino acids 34 to 159 (126 residues), 107.4 bits, see alignment E=9.7e-35 PF12627: PolyA_pol_RNAbd" amino acids 186 to 246 (61 residues), 38 bits, see alignment E=1.7e-13 PF12626: PolyA_pol_arg_C" amino acids 296 to 409 (114 residues), 98.6 bits, see alignment E=3.9e-32

Best Hits

KEGG orthology group: K00970, poly(A) polymerase [EC: 2.7.7.19] (inferred from 85% identity to acd:AOLE_16545)

Predicted SEED Role

"Poly(A) polymerase (EC 2.7.7.19)" in subsystem Polyadenylation bacterial (EC 2.7.7.19)

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.19

Use Curated BLAST to search for 2.7.7.19

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (483 amino acids)

>MPMX26_00543 Poly(A) polymerase I (Acinetobacter radioresistens SK82)
MQTLHASKCGLSTTQLPSSILDVIESLTKAGYEAYIVGGGVRDLMLGLNPKDFDAVTNAT
PSQIKDVFGRRCRIIGRRFELAHVYSGRELIEVATFRAPPKKAVTSASGMILRDNNWGSI
EQDFSRRDFSINALYYQPHKGIVLDFCDAVQDIKNKTLRLLGDPVQRFEEDPVRMLRTLR
FAAKLNFKIDPAILKIFTAELAQLLRDVSPHRLYDESQKLFTMGHLARVLPMLIDFDIWK
QLFADIRPNITAFIELAAKNTDHRIQIGKTINPAFFYAVLLWEPFLERYEFYSGKGIVAA
EARAQAGLDVLKRQATRTVIPRFAETFIREVWEMQSRLLNPKPQQIEALASHARFRAGFD
FLLLREKAGDPTTQGMGQWWDAYQNMGADEKEKTISQYNRQRAKNRRKQNEDVLDEVKHL
EIEPLVDIPEPRSRRARKARKPEVDHEAVKAAESVGDFNSDHPIMKRKRVKRDLSQVVFG
PTQ