Protein Info for MPMX26_00373 in Acinetobacter radioresistens SK82

Annotation: Putative cation/proton antiporter YbaL

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 572 transmembrane" amino acids 6 to 26 (21 residues), see Phobius details amino acids 33 to 51 (19 residues), see Phobius details amino acids 60 to 79 (20 residues), see Phobius details amino acids 88 to 111 (24 residues), see Phobius details amino acids 117 to 137 (21 residues), see Phobius details amino acids 149 to 176 (28 residues), see Phobius details amino acids 189 to 210 (22 residues), see Phobius details amino acids 230 to 263 (34 residues), see Phobius details amino acids 280 to 298 (19 residues), see Phobius details amino acids 309 to 332 (24 residues), see Phobius details amino acids 341 to 365 (25 residues), see Phobius details amino acids 372 to 391 (20 residues), see Phobius details PF00999: Na_H_Exchanger" amino acids 13 to 389 (377 residues), 219.9 bits, see alignment E=5e-69 PF02254: TrkA_N" amino acids 431 to 543 (113 residues), 65.2 bits, see alignment E=7.1e-22

Best Hits

KEGG orthology group: K03455, monovalent cation:H+ antiporter-2, CPA2 family (inferred from 88% identity to aci:ACIAD0500)

Predicted SEED Role

"TrkA-N:Sodium/hydrogen exchanger" in subsystem Potassium homeostasis

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (572 amino acids)

>MPMX26_00373 Putative cation/proton antiporter YbaL (Acinetobacter radioresistens SK82)
MPHDVDLIILLAVGFGIALIFGYIAARLRLPPLIGYLIAGIIISPNTPGMVGDIQLANQL
AELGVMFLMFGVGMHFSLNDLLQVRRIAVPGAILQITVATLLGIGISMLWGWSFGSALVF
GLSLSCASTVVLLKALGDRGLLESVNGKIAVGWLLVEDLVMVLVLVLLPATAVLLGGTPL
SDGSGDENIWLTLGLTLLKVTGFIAFMLIIGKRLVPMIMQFVARLGSRELFTLTVVAAAV
SIAYGSYAVFGVSMALGAFFAGMVVKESDFSHRAEEETLPLREIFSVLFFVSVGMLFDPR
ILVEEPVHILGVVAIIMIGKTLAAMALVLFFRYPINTALTVGASLAQIGEFSFILATLGL
SLGLLSLEGQNLILAGALISISLNSFIFSAIEPAQRWIRERSHLARLLERSGDPLAMLPD
EVSQDYLRDQVVIVGHGEVGRRITRTLMQENIKVVIAEENREIVEKLRERGIAAVSGVAT
EPGVLIQAHIMHARLLVLSPMDIVNVHRIIDIAKQLNPQIQVLICAESKEEAEVIRAENI
GEVFFAKEEMAKNMSNHILNQIEIAHHTAPTH