Protein Info for MPMX26_00273 in Acinetobacter radioresistens SK82

Annotation: RecBCD enzyme subunit RecD

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 TIGR01447: exodeoxyribonuclease V, alpha subunit" amino acids 66 to 595 (530 residues), 421.7 bits, see alignment E=2.7e-130 PF04851: ResIII" amino acids 143 to 262 (120 residues), 24.1 bits, see alignment E=1.7e-08 PF13604: AAA_30" amino acids 144 to 345 (202 residues), 94.2 bits, see alignment E=4.9e-30 PF00580: UvrD-helicase" amino acids 144 to 235 (92 residues), 30.9 bits, see alignment E=1.3e-10 PF13245: AAA_19" amino acids 145 to 295 (151 residues), 115.9 bits, see alignment E=8.8e-37 PF13401: AAA_22" amino acids 158 to 288 (131 residues), 28.7 bits, see alignment E=8.2e-10 PF09848: SLFN-g3_helicase" amino acids 158 to 325 (168 residues), 26 bits, see alignment E=3.2e-09 PF05127: Helicase_RecD" amino acids 159 to 275 (117 residues), 30.1 bits, see alignment E=2.3e-10 PF18335: SH3_13" amino acids 447 to 506 (60 residues), 41 bits, see alignment 7.3e-14 PF13538: UvrD_C_2" amino acids 525 to 571 (47 residues), 42.7 bits, see alignment 2.3e-14 PF01443: Viral_helicase1" amino acids 527 to 570 (44 residues), 26.5 bits, see alignment 3e-09

Best Hits

KEGG orthology group: K03581, exodeoxyribonuclease V alpha subunit [EC: 3.1.11.5] (inferred from 62% identity to abn:AB57_0436)

Predicted SEED Role

"Exodeoxyribonuclease V alpha chain (EC 3.1.11.5)" in subsystem DNA-replication (EC 3.1.11.5)

Isozymes

Compare fitness of predicted isozymes for: 3.1.11.5

Use Curated BLAST to search for 3.1.11.5

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>MPMX26_00273 RecBCD enzyme subunit RecD (Acinetobacter radioresistens SK82)
MDKFVYNSVDNYEDNCVENKQLHENSQQQWISTWSSFIAQTPFHDGEKHENATNIIVQVL
ETLQQGNSCIEATEDQVKVLNNLVGFEQQEHLPVAPFIFDGSSLYLYRYWNLETRLAKQI
ERLWQQQIPPVDLTAYSGLLQDKYQKSALTMVAGKILSMITGGPGTGKTYTLARIIAVLN
QVIPDIRIAMAAPTGKAAQRMQEALRHSFQDPKLLESGLVTQSLQMQTTQTIHRLLGLGQ
NQQPRFHSRQPLPYDVIVIDEASMLDLELATLLFEAIPDHCRLILLGDAQQLASVEVGSV
LADLQQIPALAEHRVHLVNSRRFTEDALIGKMAKFIQQFQAGKPHTEILDYFQQQIVPAN
QLSAITLSHDMQDQVQLEFLPASAQSLNWTEFYEKLMQGYLPYLKALKNYLQAEETSEDT
VKPLVQAFDHYRLLAATRHGALGLEKLNQYAKQWLNQALKTIAVGDWYIGRPVMMTYNDY
QLGLSNGDIGICVRHREHPDQFEVYFPSLNKWVAATRLPKNIETAFALTIHKSQGSEFTH
TTVVLDQTAKNLLSQELIYTAITRAKKVVSLLVDPEAFVQSLTVKTTRKSGLVSKINRKL
SL