Protein Info for MPMX26_00259 in Acinetobacter radioresistens SK82

Annotation: Na(+)/H(+) antiporter subunit D

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 602 transmembrane" amino acids 12 to 30 (19 residues), see Phobius details amino acids 50 to 68 (19 residues), see Phobius details amino acids 87 to 112 (26 residues), see Phobius details amino acids 124 to 142 (19 residues), see Phobius details amino acids 148 to 166 (19 residues), see Phobius details amino acids 177 to 200 (24 residues), see Phobius details amino acids 222 to 244 (23 residues), see Phobius details amino acids 252 to 273 (22 residues), see Phobius details amino acids 293 to 311 (19 residues), see Phobius details amino acids 318 to 338 (21 residues), see Phobius details amino acids 345 to 367 (23 residues), see Phobius details amino acids 388 to 409 (22 residues), see Phobius details amino acids 427 to 452 (26 residues), see Phobius details amino acids 484 to 501 (18 residues), see Phobius details PF00361: Proton_antipo_M" amino acids 143 to 431 (289 residues), 136 bits, see alignment E=8e-44

Best Hits

KEGG orthology group: K05561, multicomponent K+:H+ antiporter subunit D (inferred from 71% identity to abc:ACICU_00355)

Predicted SEED Role

"Na(+) H(+) antiporter subunit D" in subsystem Sodium Hydrogen Antiporter

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (602 amino acids)

>MPMX26_00259 Na(+)/H(+) antiporter subunit D (Acinetobacter radioresistens SK82)
MSDFLSFWHAHTPIFSIVIPLFTAVLLLLLGNPGSGELAQDWRQPWRRGISYFSALAGFA
TAISYFIQASQGTITVYNLSEWAAPFGIILVLDQLSAMMLVLTYTLAVPLLWYASKDWDT
RGRYFHAMVHFLLMGLCGAFLTGDLFNLFVFFEILLMASYVLLLHGQGKARFQLGVHYVT
INLLASALFLIGLGIIYGSVGSLNMADVARIVPSLPPDQHQLAVAGSLLLFAVFAIKAAL
LPVGFWLPKTYAVATTPVAALFTIMTKVGIYAILRVNGTIFDDYFAQTALKSWLLPLAII
TAIYGTIGAIGAERLRRFVGFMIVSSIGTLLIAISMFNTEAWSAALYYLVHSTLIGAAFY
LLCGWITSQRGEFKDHLDVSPKMKQDKTIALVYLIIGMMMAGLPPFSGFFGKLFILQATA
NHPQQGIIIASLLIVSLLSIIAFVRVGFILFWRATTPEMDPREIAFEAYKVLPETAPVRN
DKTLYLLLLLLILYVVFAAPIQRYNHNTALQIQNDQAYADTILKRGPLNQVISVKPYDAS
YVPETKYGGENKDRNANLIPFMISENTLEGGHISEYKWRQIQQQHSLEPAVPEDAQLKPM
EP