Protein Info for MPMX26_00171 in Acinetobacter radioresistens SK82

Annotation: Fe(2+) transporter FeoB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 617 transmembrane" amino acids 105 to 122 (18 residues), see Phobius details amino acids 214 to 240 (27 residues), see Phobius details amino acids 248 to 262 (15 residues), see Phobius details amino acids 273 to 298 (26 residues), see Phobius details amino acids 320 to 341 (22 residues), see Phobius details amino acids 353 to 378 (26 residues), see Phobius details amino acids 391 to 416 (26 residues), see Phobius details amino acids 454 to 473 (20 residues), see Phobius details amino acids 485 to 504 (20 residues), see Phobius details amino acids 511 to 533 (23 residues), see Phobius details amino acids 554 to 578 (25 residues), see Phobius details amino acids 590 to 612 (23 residues), see Phobius details PF01926: MMR_HSR1" amino acids 6 to 123 (118 residues), 70.4 bits, see alignment E=2.9e-23 PF02421: FeoB_N" amino acids 6 to 164 (159 residues), 190.1 bits, see alignment E=3.6e-60 TIGR00437: ferrous iron transport protein B" amino acids 209 to 583 (375 residues), 315.7 bits, see alignment E=6.9e-98 PF07670: Gate" amino acids 282 to 376 (95 residues), 77.3 bits, see alignment E=2.4e-25 amino acids 451 to 587 (137 residues), 61.6 bits, see alignment E=1.8e-20 PF07664: FeoB_C" amino acids 394 to 446 (53 residues), 53.7 bits, see alignment 2.7e-18

Best Hits

KEGG orthology group: K04759, ferrous iron transport protein B (inferred from 87% identity to abb:ABBFA_003289)

Predicted SEED Role

"Ferrous iron transport protein B" in subsystem Campylobacter Iron Metabolism or Iron acquisition in Vibrio or Transport of Iron

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (617 amino acids)

>MPMX26_00171 Fe(2+) transporter FeoB (Acinetobacter radioresistens SK82)
MSEPLRVALVGNPNCGKTSLFNHLTGTRQKVANYAGVTVERKTGFFELPSGQQVRVLDLP
GTYSLNATSPDEAITRDVVQGKITEEGQQDVFLCVVDATNLKLHLGLVMEMIELGRPILL
VLNMMDEARRRGMQINTQKLSERLGVNVVETVAVRNAGVESLINSLDQRKFDVPHTELSG
LSGSTHQKITHILKDVVNYIDEEDKRTDFFDKIFLHPVLGLLSLALMMFVIFQAVFAWAA
PFMDGIETFFGWLGETISPYISQPLLNSLVVDGIIAGAGGVVVFLPQILILFFFILVLEE
SGYLPRAAFLLDKLMFKAGLSGRAFIPLLSSFACAVPGIMATRSISDPRDRLTTILVAPL
MTCSARLPVYALLIAAFIPEQTVWGFMNLQGLVLFALYMAGIVSALLVATIMKFFYKDKS
QHTLLMELPSYRFPDIKNIWIGLLDRGKIFLKRVGGIIFALSVLLWFLCTFPQPPAGATM
PDIDYSFAGMLGHLMQPIFAPLGFNWQICIALIPAMAAREVVVAALGTVYALSATDEDAV
SQGLSQLISADGSGWSLATGLSLLVWFIYAPHCLATLATVRRETGSWKTVAFMTTYLFGL
AYFMSFLTYQIASHYFA