Protein Info for MPMX26_00157 in Acinetobacter radioresistens SK82

Annotation: cytosol aminopeptidase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 482 PF02789: Peptidase_M17_N" amino acids 38 to 135 (98 residues), 41 bits, see alignment E=1.7e-14 PF00883: Peptidase_M17" amino acids 168 to 470 (303 residues), 419.2 bits, see alignment E=1.1e-129

Best Hits

Swiss-Prot: 77% identical to AMPA_ACIB3: Probable cytosol aminopeptidase (pepA) from Acinetobacter baumannii (strain AB307-0294)

KEGG orthology group: K01255, leucyl aminopeptidase [EC: 3.4.11.1] (inferred from 77% identity to abn:AB57_0318)

Predicted SEED Role

"Cytosol aminopeptidase PepA (EC 3.4.11.1)" (EC 3.4.11.1)

KEGG Metabolic Maps

Isozymes

No predicted isozymes

Use Curated BLAST to search for 3.4.11.1

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (482 amino acids)

>MPMX26_00157 cytosol aminopeptidase (Acinetobacter radioresistens SK82)
MKLTINTSSSTLTSSQHLIILTDAENLEQPATGYQFNELKALIDATQFKGSLNECLPLIA
QTSAHQNAVLLGLDKVSEFKTAKLAKIAQTVIKSTQKKFKHITIDISALPDEFHYLFALG
LTQAAYQFDEFKSKKNEFQLEHIELVAPQSSLSQQQLTLLHAVQSGQNFARDLGNRPGNI
CFPEYLAEQAQALAAQYPDLLKVTVLNEQQMADLGMNAFLAVSKGSDRPGRVITLEYKVK
TEEAPVVLVGKGVTFDTGGISLKPGLGMDEMKFDMCGAASVLGTIRALCEAKLPIHVIGA
VAAAENMPSGHATRPGDIVTTMSGQTVEILNTDAEGRLVLCDTLTYVKRFNPALVIDIAT
LTGACVVALGKVLSGLFTPDDELAAEITRAGEQSHDRVWRMPVLDDYQEQLDSPFADMGN
IGGPQAGSVTAACFLQRFTTDYRWAHLDVAGTAWLSGAAKGATGRPVPMLMQFLANRAAA
NG