Protein Info for MPMX26_00139 in Acinetobacter radioresistens SK82

Annotation: Putative niacin/nicotinamide transporter NaiP

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 439 transmembrane" amino acids 20 to 44 (25 residues), see Phobius details amino acids 56 to 77 (22 residues), see Phobius details amino acids 84 to 104 (21 residues), see Phobius details amino acids 110 to 131 (22 residues), see Phobius details amino acids 143 to 165 (23 residues), see Phobius details amino acids 171 to 189 (19 residues), see Phobius details amino acids 253 to 273 (21 residues), see Phobius details amino acids 290 to 309 (20 residues), see Phobius details amino acids 316 to 335 (20 residues), see Phobius details amino acids 341 to 362 (22 residues), see Phobius details amino acids 374 to 395 (22 residues), see Phobius details amino acids 406 to 426 (21 residues), see Phobius details PF07690: MFS_1" amino acids 26 to 295 (270 residues), 142.2 bits, see alignment E=2.1e-45 amino acids 293 to 430 (138 residues), 45.7 bits, see alignment E=4.5e-16 PF00083: Sugar_tr" amino acids 49 to 437 (389 residues), 173.2 bits, see alignment E=9.4e-55

Best Hits

KEGG orthology group: K08369, MFS transporter, putative metabolite:H+ symporter (inferred from 83% identity to aci:ACIAD0233)

Predicted SEED Role

"Niacin transporter NiaP" in subsystem NAD and NADP cofactor biosynthesis global or NAD regulation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (439 amino acids)

>MPMX26_00139 Putative niacin/nicotinamide transporter NaiP (Acinetobacter radioresistens SK82)
MDLVSRVQRLPIGRFHYTLLWVVGLGWMFDAMDTGIIAFIMATLVKDWALTPVQSGWIVS
IGFVGMAIGAVFSGGLADRFGRRTVFATTLGVYSVATALCAVAPNLTWLLIFRFIVGLGL
GGQLPVAVTLVSEYVPAHVRGRFIVLLESFWGLGWLVAALISYFIIPSFGWHVAFLIGGL
PALYIFIILKKVPESVPYLINRGRINEAHILVQQLERQCGVEVVETLEVQPVASQKSVSF
KQLWSGQFARRSLMLWLIWFGIVYSYYGIFTWLPSLLVKQGYSIVQSFEYVLIMILAQLP
GYIVAAWLVEKLGRKITLAGFIGFCAVSAYFFGQASSVSMIMFWGCLMSFFNLGAWGVLY
TYTPEQYPANIRAFGSGWASAVGRMGGILAPLVVTQMMVADHGFSHVFLMFTLVLVTVAL
VIIILGEETKGKTLESIGL