Protein Info for MPMX26_00118 in Acinetobacter radioresistens SK82

Annotation: Vitamin B12 transporter BtuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 687 signal peptide" amino acids 1 to 27 (27 residues), see Phobius details TIGR01778: TonB-dependent copper receptor" amino acids 55 to 687 (633 residues), 747.2 bits, see alignment E=9.6e-229 PF07715: Plug" amino acids 60 to 150 (91 residues), 49.1 bits, see alignment E=7.6e-17 PF00593: TonB_dep_Rec_b-barrel" amino acids 207 to 647 (441 residues), 121.2 bits, see alignment E=1.1e-38

Best Hits

KEGG orthology group: K02014, iron complex outermembrane recepter protein (inferred from 70% identity to aby:ABAYE3703)

Predicted SEED Role

"Putative membrane receptor protein"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (687 amino acids)

>MPMX26_00118 Vitamin B12 transporter BtuB (Acinetobacter radioresistens SK82)
MARPKFFLQPLSAAIFIACYSGTLFAETETSVQTLAPIIITAQQGNEASGLIVQADPKKP
IQPVPATDGADYLQSIVGFSAIKNGGTNGDVTFRGMFGSRIKILTDGTENLGACPSRMDA
PTSYIQPESYDQISVIKGPQTVQYAQTGSAATVIFERKPVRFNEDQHYQGQASTMLGSFG
RLDHNVEAAVGDENKYIRLNANRSKSDSYKDGDGNTVPSAWERWNTDLALGWTPDEQTWL
ELTAGKSDGEALYAGRDMDGSQFARESLGLRFEKNNINDVIKKIEGQVNYSYNDHIMDNF
SLRTPPLVEMTHSGMTMLMPDPQEMQVTRRTLNTRLAVTTAWNQANIISGIDSQHNHHAG
GMTSMMMNMPLTTNMKFQSYGAFSELSYPFNEHYKLVTGARIDQIKIDALKLDENRKETL
PSAFVRLEGQHPEHDAKTYIGLGYVQRAPDYWELFSTAHGNTGMGKPTFNDLDTEKTLQL
DLGYQHQHGAFSSWLSAYTGLINDYILISYHDHPAAGAHGHGSNFSAGAKNIDAVIAGAE
AGVGYQLTDAVQADLSTMYAWGKNTTDHTPLPQIAPLEGRFNLRYVQDKYTLGLLWRMVA
QQDRISLNQGNIVGYDLQKSKGFSTLSLNGSYSLMQHVDLALGIDNVLNKTYTEHLNRAG
SSGFGFASHEQFNNMGRNYWARVSIKF