Protein Info for MPMX26_00093 in Acinetobacter radioresistens SK82

Annotation: High-affinity zinc uptake system membrane protein ZnuB

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 267 transmembrane" amino acids 7 to 31 (25 residues), see Phobius details amino acids 45 to 77 (33 residues), see Phobius details amino acids 86 to 106 (21 residues), see Phobius details amino acids 124 to 145 (22 residues), see Phobius details amino acids 169 to 186 (18 residues), see Phobius details amino acids 192 to 209 (18 residues), see Phobius details amino acids 216 to 234 (19 residues), see Phobius details amino acids 239 to 259 (21 residues), see Phobius details PF00950: ABC-3" amino acids 6 to 259 (254 residues), 184.9 bits, see alignment E=1e-58

Best Hits

Swiss-Prot: 38% identical to ZNUB_HAEIN: High-affinity zinc uptake system membrane protein ZnuB (znuB) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd)

KEGG orthology group: K09816, zinc transport system permease protein (inferred from 82% identity to abc:ACICU_00167)

MetaCyc: 38% identical to Zn2+ ABC transporter membrane subunit (Escherichia coli K-12 substr. MG1655)
ABC-63-RXN [EC: 7.2.2.20]

Predicted SEED Role

"Zinc ABC transporter, inner membrane permease protein ZnuB" in subsystem Transport of Zinc

Isozymes

No predicted isozymes

Use Curated BLAST to search for 7.2.2.20

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (267 amino acids)

>MPMX26_00093 High-affinity zinc uptake system membrane protein ZnuB (Acinetobacter radioresistens SK82)
MMEWLQLLLPAWIMGTLLVFLTAPLGCLMLWRRMSFFADTMAHGTLLGVAVAGALSLPLW
MGVTLLALLLVAVLWVLHDPRLPSDALLALCSATLLCSGLLFIQHLPSLRPELLSYLFGD
LLTISWNDLPTFAAVILLALAVLYKSWQAQIRTAIDPDIAASEGIHNQWQRLIFMLLLAL
FTVLALRAVGSLLMGALLVIPALTARLLAHSPRQMVIWAFVMAQIGITVGLWSSAGLDIS
TGLSIVLTMAILFILIFTVQKIRTSIS