Protein Info for MPMX26_00062 in Acinetobacter radioresistens SK82

Annotation: UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 624 transmembrane" amino acids 17 to 39 (23 residues), see Phobius details amino acids 51 to 75 (25 residues), see Phobius details amino acids 83 to 103 (21 residues), see Phobius details amino acids 108 to 128 (21 residues), see Phobius details PF13727: CoA_binding_3" amino acids 70 to 230 (161 residues), 33 bits, see alignment E=1.9e-11 PF01370: Epimerase" amino acids 286 to 474 (189 residues), 75.4 bits, see alignment E=1.4e-24 PF02719: Polysacc_synt_2" amino acids 286 to 573 (288 residues), 409.2 bits, see alignment E=2.8e-126 PF04321: RmlD_sub_bind" amino acids 286 to 454 (169 residues), 34.6 bits, see alignment E=3.3e-12 PF16363: GDP_Man_Dehyd" amino acids 287 to 410 (124 residues), 47 bits, see alignment E=7.6e-16 PF01073: 3Beta_HSD" amino acids 287 to 414 (128 residues), 37.5 bits, see alignment E=4.5e-13

Best Hits

KEGG orthology group: None (inferred from 74% identity to aby:ABAYE3804)

Predicted SEED Role

"Nucleoside-diphosphate sugar epimerase/dehydratase"

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Compare to protein structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (624 amino acids)

>MPMX26_00062 UDP-N-acetyl-alpha-D-glucosamine C6 dehydratase (Acinetobacter radioresistens SK82)
MKSIITPFVESPRAAKLAFLIILDFCAFPVLIWLCYAIRRFDLGAEVVPNLAFGTLWVSV
IAVTALFSCGVYRFIVRTYNEVFMIKMGLATALTVAGLYALAYFTPAFIPTSIPLMFGFM
MFAWIWFSRGIIRFIIRSYLQADVQKKRIAIYGAGHAGQQVAAALYRSNAHLPVMFIDDK
RSLTGQQLGRLKVYDAQTALKLMSKQKIDEILIALPSVGRVRKSEIIKFLEPAHLKITEI
PGLTKLVDGEIRISDIQEVDIIDLLGRDPVPPVPELLVRNIQDKVVMVTGAGGSIGSELC
RQIVKNQPTKIVIFELTEFALYNIDKELRLMSQCEIIPILGSVLDQQKLERVIEQYAVQT
VYHAAAYKHVPLVECNPLAGLKNNAVGTAFSVNAAVKKGVETFVLISTDKAVRPTNVMGA
SKRMAELYCQAMAEAQQQTQISIVRFGNVLGSSGSVVPLFKQQILKGGPITVTHPDVTRY
FMTIPEASQLVIQAGALGVGGDVFLLDMGEPVRIQDLARQMIALSGLKVRDEQHPEGDIE
IQYAGLRPGEKLYEELLIDHDNTQITEHSRILRSFEKHYTFNELLPVFERIHNMTAIQTD
IDWALGQLEYYVDGYKRSGLVSVN