Protein Info for MPMX19_06854 in Azospirillum sp. SherDot2

Annotation: Acetylornithine deacetylase

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• TIGR01892: acetylornithine deacetylase (ArgE)
  • amino acids 5 to 368 (364 residues), 457.9 bits, E=1.3e-141
• PF01546: Peptidase_M20
  • amino acids 66 to 368 (303 residues), 123.8 bits, E=9.2e-40
• PF07687: M20_dimer
  • amino acids 170 to 273 (104 residues), 76.2 bits, E=1.8e-25

Best Hits

KEGG orthology group: K01438, acetylornithine deacetylase [EC: 3.5.1.16] (inferred from 89% identity to azl:AZL_c03170)

Predicted SEED Role

"Acetylornithine deacetylase (EC 3.5.1.16)" in subsystem Arginine Biosynthesis extended (EC 3.5.1.16)

MetaCyc Pathways

• L-arginine biosynthesis I (via L-ornithine) (9/9 steps found)
• superpathway of arginine and polyamine biosynthesis (14/17 steps found)
• L-arginine biosynthesis III (via N-acetyl-L-citrulline) (8/9 steps found)
• L-ornithine biosynthesis I (5/5 steps found)

KEGG Metabolic Maps

• Arginine and proline metabolism
• Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
• Urea cycle and metabolism of amino groups

Isozymes

Compare fitness of predicted isozymes for: 3.5.1.16

Use Curated BLAST to search for 3.5.1.16

Protein Sequence (374 amino acids)

>MPMX19_06854 Acetylornithine deacetylase (Azospirillum sp. SherDot2)
MTVTDILKDLIAFPSVVGTPNGAIVDGIRGILEAAGVRVRVLPGPEGDRFNLFATIGPAM
VPGYVLSGHMDVVPATEPEWTGDPFRLRTDGNRLYGRGTSDMKGFIAAALAALPALTAAP
LARPIHLAFTYDEEAGCQGAPHLLPHLPDLCAPPLGVIVGEPSGLRAVRAHKGKASARLT
VRGRSGHSSRPDQGLNAIHAMTDALTAAVAQAGRLSDGPLDSVFEPPYSSLQAGTIQGGL
AVNVIPDTCTAEFEARAIAGVDPVSLLEPVREAALRLEQRGFAVDWTQTSAYPALFLAAR
SPLARLLEELTGREPQAAISYGTEAGLYQTAGIDAIICGPGDIARAHRPDEHILVEELHA
CQSMIEALGQRCRL