Protein Info for MPMX19_06834 in Azospirillum sp. SherDot2

Annotation: Vitamin B6 salvage pathway transcriptional repressor PtsJ

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 461 PF00392: GntR" amino acids 16 to 78 (63 residues), 54.1 bits, see alignment E=1.9e-18 PF13545: HTH_Crp_2" amino acids 39 to 77 (39 residues), 29.7 bits, see alignment 1e-10 PF13412: HTH_24" amino acids 40 to 68 (29 residues), 24.3 bits, see alignment (E = 3.7e-09) PF00155: Aminotran_1_2" amino acids 152 to 445 (294 residues), 75.9 bits, see alignment E=7.3e-25

Best Hits

KEGG orthology group: None (inferred from 60% identity to rhi:NGR_b23330)

Predicted SEED Role

"Transcriptional regulator GabR of GABA utilization (GntR family with aminotransferase-like domain)" in subsystem Threonine degradation

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (461 amino acids)

>MPMX19_06834 Vitamin B6 salvage pathway transcriptional repressor PtsJ (Azospirillum sp. SherDot2)
MTKWHPDASALSRPVYLSLADQVQRAITQGQLAVGDQLPTHRQLADELGISVQTVSRAYE
ELIRRGLISGETGRGTFIRAAQTEVDPPYIPQRTDEVIDLSILKPVCEPLHVEAMRGALV
ELAASLPPAVVLSFRPNTLFARHRATAVSWLRHCGVETTAANVTLTNGATAGMTIALMAA
APPGSTVVTEEVGHHTLLPLASYLGIKLRGVAIDEDGIRPDALDAACRDGTAKALFVMPN
PINATATHMGEERRREIARLAQRHNLSIVENDPLGPLLSERRPPLAALAPERTLYVTSFT
KTVMPGLRTGYLVVPDRLLAAVTNRHLVTNWIATPIVAEIATRWVESGFAMEMVEWQRKA
LHRRHALAAELLKGIPHRSHPEGLHLWLPLGEGRPEATFVSHARHQGVALAPGSAFAIGP
GTRPDALRVSIGSTTEAELHTGLRVIVNLLNSDPEPVLLAM