Protein Info for MPMX19_06804 in Azospirillum sp. SherDot2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

• PF02558: ApbA
  • amino acids 4 to 104 (101 residues), 65.7 bits, E=3.8e-22
• PF08546: ApbA_C
  • amino acids 197 to 316 (120 residues), 92 bits, E=3.8e-30

Best Hits

KEGG orthology group: K00077, 2-dehydropantoate 2-reductase [EC: 1.1.1.169] (inferred from 64% identity to ade:Adeh_2270)

Predicted SEED Role

"2-dehydropantoate 2-reductase (EC 1.1.1.169)" in subsystem Coenzyme A Biosynthesis (EC 1.1.1.169)

MetaCyc Pathways

• superpathway of coenzyme A biosynthesis I (bacteria) (8/9 steps found)
• phosphopantothenate biosynthesis I (4/4 steps found)
• superpathway of coenzyme A biosynthesis II (plants) (7/10 steps found)
• phosphopantothenate biosynthesis III (archaea) (2/4 steps found)

KEGG Metabolic Maps

• Pantothenate and CoA biosynthesis

Isozymes

Compare fitness of predicted isozymes for: 1.1.1.169

Use Curated BLAST to search for 1.1.1.169

Protein Sequence (328 amino acids)

>MPMX19_06804 hypothetical protein (Azospirillum sp. SherDot2)
MKTCIIGAGAIGGLIGIRLAQAGCDVSVLARGATADALRAGPWRLAAADGQVAASVRVAD
DLTALGPQELVVIAVKGQSLPGLAPSLTPLIGTETMVLPAMNGVPWWFFHRFGGPLAGMP
LDSVDPGRRIAAAIPDEAVVGCVVHATCSVAEPGLVRHGFGNRLIVGEPDGSLSPRLGRL
ADCLTAAGFEILSSPRIQTDIWYKLWGNMTMNPVSALTGATCDRILDDPLVSGFCLSVMA
EAAELGRLIGCPIEQSGEDRNAVTRRLGAFKTSMLQDAEAGKPLEIDALLGAVKEIAGRL
GQATPNLDALLGLTRLMAGTRGLHPAMD