Protein Info for MPMX19_06715 in Azospirillum sp. SherDot2

Annotation: hypothetical protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 482 TIGR03915: probable DNA metabolism protein" amino acids 11 to 247 (237 residues), 186.3 bits, see alignment E=7.6e-59 PF13566: DUF4130" amino acids 80 to 246 (167 residues), 125.1 bits, see alignment E=2.5e-40 TIGR03914: uracil-DNA glycosylase family domain" amino acids 250 to 473 (224 residues), 285.4 bits, see alignment E=3.4e-89 PF03167: UDG" amino acids 315 to 471 (157 residues), 104 bits, see alignment E=7.5e-34

Best Hits

KEGG orthology group: K02334, DNA polymerase bacteriophage-type [EC: 2.7.7.7] (inferred from 61% identity to mrd:Mrad2831_3539)

Predicted SEED Role

"Domain often clustered or fused with uracil-DNA glycosylase / Uracil-DNA glycosylase, putative family 6"

KEGG Metabolic Maps

Isozymes

Compare fitness of predicted isozymes for: 2.7.7.7

Use Curated BLAST to search for 2.7.7.7

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (482 amino acids)

>MPMX19_06715 hypothetical protein (Azospirillum sp. SherDot2)
MRHVELRDGADLDGFRRALRGLVALGADPDGVVWSGGAAPSLFGTAPETGTAPLPADAPP
VPLPRPVGALIESVVCHRDPERYALLHRLVCRVVRGERDILDHHADPLVHRLALLDKAVR
RDLHKMHAFLRFREVRDPANSEDRGGERYVAWFEPDNFIVEATASFFVERFESLVWTILT
PVGSLHWDRRSLTVGPAALRPEGLDRDDRFAEGWQRYYESTFNPARVNPTAMRAEMPRKY
WANLPEAAAIPGMIRGAPARVQAMIEAEAAAPRRRNPDKAVAAMARQEPATLAELNRIIR
AADPLVPGATQAVLGEGPVGAAIAIVGEQPGDREDMEGRPFVGPAGQLLTRALEEAGIER
DAAYLTNAVKHFKFVARGKRRLHQSPTAGEVKHYRWWLMKELGFVRPRLVVTLGATAALA
LSGRSVSVLRERGPMGFGDWEGLVTVHPSYLLRLPAGEGAEQAYRDFVADLRRARGMVEG
TG