Protein Info for MPMX19_06556 in Azospirillum sp. SherDot2

Annotation: Toxin RTX-I translocation ATP-binding protein

These analyses and tools can help you predict a protein's function, but be skeptical. For enzymes, over 10% of annotations from KEGG or SEED are probably incorrect. For other types of proteins, the error rates may be much higher. MetaCyc and Swiss-Prot have low error rates, but the best hits in these databases are often quite distant, so this protein's function may not be the same. TIGRFam has low error rates. Finally, many experimentally-characterized proteins are not in any of these databases. To find relevant papers, use PaperBLAST.

Protein Families and Features

1 50 100 150 200 250 300 350 400 450 500 550 600 650 700 762 transmembrane" amino acids 192 to 213 (22 residues), see Phobius details amino acids 226 to 246 (21 residues), see Phobius details amino acids 302 to 324 (23 residues), see Phobius details amino acids 330 to 350 (21 residues), see Phobius details amino acids 428 to 448 (21 residues), see Phobius details PF03412: Peptidase_C39" amino acids 47 to 160 (114 residues), 32.9 bits, see alignment E=8.1e-12 TIGR01846: type I secretion system ATPase" amino acids 49 to 742 (694 residues), 984.5 bits, see alignment E=1.4e-300 PF00664: ABC_membrane" amino acids 192 to 458 (267 residues), 196 bits, see alignment E=1.6e-61 PF00005: ABC_tran" amino acids 522 to 671 (150 residues), 120.3 bits, see alignment E=1.5e-38

Best Hits

KEGG orthology group: K11004, ATP-binding cassette, subfamily B, bacterial HlyB/CyaB (inferred from 61% identity to bja:bll6293)

Predicted SEED Role

"cyclolysin secretion ATP-binding protein" in subsystem cAMP signaling in bacteria

Sequence Analysis Tools

PaperBLAST (search for papers about homologs of this protein)

Search CDD (the Conserved Domains Database, which includes COG and superfam)

Search structures

Predict protein localization: PSORTb (Gram-negative bacteria)

Predict transmembrane helices and signal peptides: Phobius

Check the current SEED with FIGfam search

Find homologs in fast.genomics or the ENIGMA genome browser

Find the best match in UniProt

Protein Sequence (762 amino acids)

>MPMX19_06556 Toxin RTX-I translocation ATP-binding protein (Azospirillum sp. SherDot2)
MEQMRDGSPADPARDPSSPPPGPPPPGAQTDPNPGANPGPNPGPRLDPGIAGLVSALRIL
GIPADYDGVRHACGGESPDLTGLVRQAHRLGAKARVVKTKWERLERTPLPALVPGPDGGF
LVLAKAGGDRVLVHDAATNQTRILDREGFEPLWTGRLICLGRKGTMGMGQPRFDARWFGA
VAWKYRGILGEVLLASFFIQLFALVTPLFFQVVVDKVVVHRSLGTLDVLMAGMLAVILFE
AVLGGLRTYTFAHTANRLDVELGAKLYQRLLSLPMGYFASRRVGDSVARVRELETIRNFM
TSSTITLVLDLLFTVVFLGVMLVYSPMLTAIVAASFPVYVAISLVATPILRRRLDEKFAR
GAENHSFLVETVSSIETVKAMAVEPRMQRRWEDQLSGYVRAGFRAGNLNNVASQSVQFVS
KISTMLVLWLGAKLVIEGSLTVGELVAFNMFAGRVVQPVLRIAQLWQDFQQVRLSMHRIG
DILNTAPEPLQSAGRAAMPAIKGDLSFDHVTFRYRHDGPETLSDVSLHIPAGQVVGIVGT
SGSGKSTLAKLLQRFHVPERGRVMVDGTDLSTADAVWLRRQIGVVLQDNVLFSGTIRENI
ALTDPTMDMARVVAAAKLAGAHDFVVELPDGYDTVVGERGASLSGGQRQRIAIARALVTN
PRILIFDEATSALDHESERIIQANMRRICAGRTVLIIAHRLSTVAIADRIVTVERGRIVE
DGAPDELLRRGGRYATLFRGQMGQLPGSAPPADGLIEQRAAG